How to review a reaction for green chemistry

Select the reaction and choose Object › Chemistry › Green chemistry. Each step shows its atom economy (AE) and any flags on what is written, such as a solvent the CHEM21 guide ranks poorly.

Steps

  1. Draw the reaction, with conditions over the arrow if you have them, and select it.

  2. Choose Main menu › Object › Chemistry › Green chemistry.

  3. Each step is listed with its equation and AE, its atom economy, followed by anything worth flagging.

    Green chemistry for ethanol and acetic acid to ethyl acetate: AE 83%, nothing to flag.Green chemistry for ethanol and acetic acid to ethyl acetate: AE 83%, nothing to flag.

How it is worked out

  • Atom economy counts the reactants drawn left of the arrow at one equivalent each, and the heaviest product as the main one. Reagents written over the arrow are not counted.
  • Solvents are rated by the CHEM21 selection guide (Prat et al., Green Chem. 2016). A solvent the guide does not rank is not rated.
  • Hazards and other flags are rules over what is written, so a step with nothing written says nothing.

To pick a better solvent, see the Solvent selector.

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Last updated Nov 12, 2026