Athanor by arbastro
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How to review a route for scale-up

Select the reaction or route and choose Object › Chemistry › Scale-up review. It counts the steps and longest linear sequence and lists the steps to look at, with the reason for each.

Steps

  1. Select the reaction or route.

  2. Choose Main menu › Object › Chemistry › Scale-up review.

  3. The summary gives the number of steps, the longest linear sequence, whether the route is linear, and how many steps to look at. Each step follows with what stands out.

    Scale-up review of a one-step route: 1 step, linear, 0 steps to look at.Scale-up review of a one-step route: 1 step, linear, 0 steps to look at.

What it checks

Flag Source
Energetic groups Bretherick's Handbook of Reactive Chemical Hazards
Alkylating agents ICH M7
Residual metals ICH Q3D
Other process cautions Anderson, Practical Process Research and Development

Note

Flags are reasons to look, read from the conditions as written and the structures as drawn, not verdicts: plants run cryogenic and hydrogenation steps every day. There is no cost ranking, which would need real prices at scale.

Reactions and arrowsHow to draw a reaction schemeDraw or insert the reactants, press W and drag a reaction arrow after them, write the conditions above it with the Text tool, then add the products after the arrow. Or press / and type the whole reaction as reaction SMILES.

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Last updated Nov 12, 2026