Athanor by arbastro
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How to score synthetic accessibility

Select one structure and choose Object › Chemistry › Synthetic accessibility (SA score). Athanor reports a score from 1 (easy) to 10 (hard), such as 1.6 for aspirin.

Steps

  1. Select one structure, for example aspirin.

  2. Choose Main menu › Object › Chemistry › Synthetic accessibility (SA score).

  3. The score appears at the bottom of the canvas: "SA score 1.6 of 10: easy to make."

    Aspirin selected, with SA score 1.6 of 10: easy to make.Aspirin selected, with SA score 1.6 of 10: easy to make.

Prediction

The SA score is an estimate (Ertl and Schuffenhauer, J. Cheminform. 2009), not a route. How it is computed is in Compound info.

With more than one structure selected, Athanor asks you to select one.

Names, properties and checksHow to calculate molecular weight, logP and other propertiesSelect the structure and choose Object › Chemistry › Calculate properties. The Compound info panel opens at Calculated, with the formula, exact mass, TPSA, donors, acceptors, rotatable bonds and the Lipinski rule-of-five checks.Compound info and the LibraryThe Compound info panelSelect a structure and press I (or click the Compound info tab beside Properties). The panel says what the structure is, its other names, CAS number and PubChem record, its systematic name, its InChI and SMILES, and calculated properties.

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Last updated Nov 12, 2026