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Meloxicam

Athanor · official

C14H13N3O4S2 · 351.4 g/mol

IUPAC name: 4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-1lambda6,2-benzothiazine-3-carboxamide

Also called Mobic, NSAID, oxicam

DrugsRings
Open in Athanor
The structure of Meloxicam
Drawn from its SMILES with RDKit
Acute toxicityHealth hazardDangerToxic if swallowed · May damage fertility or the unborn child · Harmful to aquatic life with long lasting effects

Names and identifiers

IUPAC name
4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-1lambda6,2-benzothiazine-3-carboxamide
Synonyms
Mobic, NSAID, oxicam
+ 37 more

Metacam, Mobicox, Movalis, Movatec, Mobec, Coxicam, Meloxivet, Melfax, UH-AC 62XX, Meloxicamum, Meloxidolor, Meloxoral, Rheumocam, Vivlodex, Melosus, RevitaCAM, Acticam, Contacera, Emdocam, Flexicam, Inflacam, Loxicom, Melovem, Meloxidyl, Recocam, DTXSID1020803, UHAC-62XX, 4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide, VG2QF83CGL, UH-AC-62 XX, ANJESO, CHEBI:6741, QMIIZ ODT, N-1539, DTXCID70803, miloxicam, N1539

Molecular formula
C14H13N3O4S2
Empirical formula
C14H13N3O4S2
Molecular weight
351.4 g/mol
Exact mass
351.03475
CAS number
71125-38-7
PubChem CID
54677470
Canonical SMILES
CC1=CN=C(S1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O
Isomeric SMILES
CC1=CN=C(S1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O
InChI
InChI=1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,18H,1-2H3,(H,15,16,19)
InChIKey
ZRVUJXDFFKFLMG-UHFFFAOYSA-N
Molfile

Names, InChI and the identifiers from PubChem, retrieved 2026-10-14.

Physical properties

Appearance
Pastel yellow solid[1]
Solubility in water
Very slightly soluble in methanol. Practically insoluble in water, with higher solubility observed in strong acids and bases.[1]
log P
log Kow = 3.54[1]

Each value as its source reports it, with the source's number after it (listed under References). Where several sources report a property, the row shows the value most of them agree on, the rule the app uses; open the values to see every one.

Calculated

Heavy atoms
23
Rings
3
Aromatic rings
2
Fraction sp³ carbons (Fsp3)
0.14
H-bond donors
2
H-bond acceptors
6 computed here · PubChem 7
Rotatable bonds
2
TPSA (Ų)
99.6 computed here · PubChem 136
Formal charge
0
XLogP3
3 PubChem
Complexity
628 PubChem
Stereocenters
None
Double-bond geometry
None specified
Point group
C1 of one 3D conformer with its hydrogens, by Athanor’s engine (as in the app)

Elemental analysis

  • C47.85%
  • H3.73%
  • N11.96%
  • O18.21%
  • S18.25%

Isotope pattern

100%351.03518%352.03711%353.0321.8%354.034355.031

Each peak is a nominal mass with its abundance-weighted exact mass, as a percentage of the tallest, from IUPAC natural isotope abundances.

Computed from the structure with RDKit 2026.09 when this page was built, beside PubChem's own computed values from its record; where the two differ, both are shown.

Predicted

log P
1.95 Crippen (Wildman and Crippen 1999)
log S (water solubility)
-3.47 ESOL (Delaney 2004), log mol/L
Synthetic accessibility
2.66 SA score, 1 easy to 10 hard (Ertl and Schuffenhauer 2009)

Drug-likeness: Lipinski’s rule of five

  • Molecular weight ≤ 500: 351.41
  • log P ≤ 5 (Crippen): 1.95
  • H-bond donors ≤ 5: 2
  • H-bond acceptors ≤ 10: 6

Passes all four rules.

¹³C NMR shifts, predicted

Predictions, not measurements; each names its method. A measured log P, where a source reports one, is under Physical properties.

Safety

Danger

Most widely reported: 118 company reports to ECHA. Source [2].

  • Acute toxicity
  • Health hazard
  • H301Toxic if swallowed (95.8% of reports)
  • H360May damage fertility or the unborn child (50.8% of reports)
  • H412Harmful to aquatic life with long lasting effects (56.8% of reports)

Precautionary statements: P203, P264, P270, P273, P280, P301+P316, P318, P321, P330, P405, P501

View all classifications (2)
  • [2] European Chemicals Agency (ECHA)This chemical does not meet GHS hazard criteria for 0.8% (1 of 118) of reports.
  • [2] European Chemicals Agency (ECHA) · 118 reports · DangerH301, H360, H412

Storage

  • Store at 25 °C (77 °F); excursions permitted to 15-30 °C (59-86 °F).[1]

Safety data sheets on the supplier’s page: Alinda Chemical Trade Company Ltd, Quality Control Solutions (QCS Standards), Vitas-M Laboratory.

Always read the supplier’s safety data sheet before working with it.

Spectra

Experimental spectra held by these sources; each link opens the source's own record.

Literature

Reading PubChem, OpenAlex and GSRS…

Bioactivity

Reading ChEMBL…

References

  1. [1]Hazardous Substances Data Bank (HSDB) · Public domain (US NLM) · via PubChem · retrieved 2026-10-14
  2. [2]European Chemicals Agency (ECHA) · ECHA legal notice: reuse with acknowledgement · via PubChem · retrieved 2026-10-14
  3. [3]SpectraBase · Linked only · via PubChem · retrieved 2026-10-14
  4. [4]Human Metabolome Database (HMDB) · Linked only · via PubChem · retrieved 2026-10-14
  5. [5]MassBank Europe · Linked only · via PubChem · retrieved 2026-10-14
  6. [6]MassBank of North America (MoNA) · CC BY 4.0 · via PubChem · retrieved 2026-10-14
  7. ·Calculated values: computed by Athanor with RDKit 2026.09 from the structure.
  8. ·Literature on PubChem

Data last updated 2026-10-14.