Ethylamine
Athanor · official
C2H7N · 45.08 g/mol
IUPAC name: ethanamine
Also called aminoethane
Names and identifiers
- IUPAC name
- ethanamine
- Synonyms
- aminoethane, Ethanamine, Aminoethane
+ 36 more
Monoethylamine, 1-Aminoethane, Aethylamine, Etilamina, Etyloamina, YG6MGA6AT5, AI3-24228, DTXSID8025678, FEMA NO. 4236, CHEBI:15862, Ethylamine (anhydrous), RefChem:5816, DTXCID005678, 200-834-7, Ethyl amine, 1,1,2,2,2-pentadeuterioethanamine, MFCD00008160, Ethylamine Solution (2.0 M in MeOH), C2H5NH2, Ethylamin, ethane, amino-, Ethylamine, 97%, Ethylamine Solution (2.0 M in THF), Etilamina [Italian], Etyloamina [Polish], Ethamine, Aethylamine [German], Ethylamine (50-70% in aqueous solution), CCRIS 6261, HSDB 803, EINECS 200-834-7, UNII-YG6MGA6AT5, UN1036, UN2270, ethaneamine, ethyamine
- Molecular formula
- C2H7N
- Empirical formula
- C2H7N
- Molecular weight
- 45.08 g/mol
- Exact mass
- 45.05785
- CAS number
- 75-04-7
- PubChem CID
- 6341
- Canonical SMILES
- CCN
- Isomeric SMILES
- CCN
- InChI
- InChI=1S/C2H7N/c1-2-3/h2-3H2,1H3
- InChIKey
- QUSNBJAOOMFDIB-UHFFFAOYSA-N
- Molfile
Names, InChI and the identifiers from PubChem, retrieved 2026-10-14.
Physical properties
- Appearance
- Colorless gas or water-white liquid (below 62 degrees F) [Shipped as a liquefied compressed gas][6]
8 values
From Hazardous Substances Data Bank (HSDB), the most authoritative source here.
Value As written Source – Ethylamine appears as a colorless liquid or a gas (boiling point 62 °F) with an odor of ammonia. Flash point less than 0 °F. Density of liquid 5.7 lb / gal. Corrosive to the skin and eyes. Vapors are heavier than air. Produces toxic oxides of nitrogen during combustion. Exposure of the closed container to intense heat may cause it to rupture violently and rocket. [1] CAMEO Chemicals – Ethylamine, aqueous solution, with not less than 50% but not more than 70% ethylamine appears as an aqueous solution of a gas. Odor ranges from fishlike to ammonia-like as the vapor concentration increases. Corrosive to skin and eyes. Less dense than water. Vapors are heavier than air. Produces toxic oxides of nitrogen during combustion. [1] CAMEO Chemicals – Gas Vapor; Liquid [2] EPA Chemical Data Reporting (CDR) – COLOURLESS COMPRESSED LIQUEFIED GAS WITH PUNGENT ODOUR. [3] ILO-WHO International Chemical Safety Cards (ICSCs) – COLOURLESS SOLUTION IN WATER WITH PUNGENT ODOUR. [3] ILO-WHO International Chemical Safety Cards (ICSCs) – Colorless gas or water-white liquid (below 62 °F) with an ammonia-like odor. [4] Occupational Safety and Health Administration (OSHA) – Colorless gas or water-white liquid (below 62 °F) with an ammonia-like odor. [Note: Shipped as a liquefied compressed gas.] [5] The National Institute for Occupational Safety and Health (NIOSH) –shown Colorless gas or water-white liquid (below 62 degrees F) [Shipped as a liquefied compressed gas] [6] Hazardous Substances Data Bank (HSDB)cites NIOSH. NIOSH Pocket Guide to Chemical Hazards. Department of Health & Human Services, Centers for Disease Control & Prevention. National Institute for Occupational Safety & Health. DHHS (NIOSH) Publication No. 2010-168 (2010). Available from: https://www.cdc.gov/niosh/npg - Melting point
- -80.6 °C[7]
6 values
5 of 5 sources agree on it (most common value).
Value As written Source −81 °C -114 °F (NTP, 1992) [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina. −81 °C -81 °C [3] ILO-WHO International Chemical Safety Cards (ICSCs) −81 °C -81 °C [3] ILO-WHO International Chemical Safety Cards (ICSCs) −81 °C -114 °F [4] Occupational Safety and Health Administration (OSHA) −80.6 °Cshown -80.6 °C [7] PAC Chemical Database, U.S. Department of Energy −81 °C -114 °F [5] The National Institute for Occupational Safety and Health (NIOSH) - Boiling point
- 16.6 °C[3]
6 values
5 of 5 sources agree on it (most common value).
Value As written Source 16.6 °C 61.9 °F at 760 mmHg (NTP, 1992) [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina. 16.6 °Cshown 16.6 °C [3] ILO-WHO International Chemical Safety Cards (ICSCs) 17 °C 17 °C [3] ILO-WHO International Chemical Safety Cards (ICSCs) 17 °C 62 °F [4] Occupational Safety and Health Administration (OSHA) 16.6 °C 16.6 °C @760 [mm Hg] [7] PAC Chemical Database, U.S. Department of Energy 17 °C 62 °F [5] The National Institute for Occupational Safety and Health (NIOSH) - Density
- 0.687 at 15 °C (59 °F) (USCG, 1999) - Less dense than water[1]
7 values
4 of 5 sources agree on it (most common value).
Value As written Source –shown 0.687 at 59 °F (USCG, 1999) - Less dense than water [1] CAMEO Chemicalscites U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office. – Relative density (water = 1): 0.7 (liquid) [3] ILO-WHO International Chemical Safety Cards (ICSCs) – Relative density (water = 1): 0.81 [3] ILO-WHO International Chemical Safety Cards (ICSCs) – 0.69 (liquid) [4] Occupational Safety and Health Administration (OSHA) – 0.662 @ 20°C [7] PAC Chemical Database, U.S. Department of Energy – 0.69 (Liquid) [5] The National Institute for Occupational Safety and Health (NIOSH) – 1.61(relative gas density) [5] The National Institute for Occupational Safety and Health (NIOSH) - Solubility in water
- Solubility in water: miscible[3]
3 values
From ILO-WHO International Chemical Safety Cards (ICSCs), the most authoritative source here.
Value As written Source – Very soluble (NTP, 1992) [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina. –shown Solubility in water: miscible [3] ILO-WHO International Chemical Safety Cards (ICSCs) – Miscible [5] The National Institute for Occupational Safety and Health (NIOSH) - log P
- -0.27/-0.08 (calculated)[3]
2 values
Sources disagree; from ILO-WHO International Chemical Safety Cards (ICSCs), the most authoritative.
Value As written Source – log Kow = -0.13 [6] Hazardous Substances Data Bank (HSDB)cites Hansch, C., Leo, A., D. Hoekman. Exploring QSAR - Hydrophobic, Electronic, and Steric Constants. Washington, DC: American Chemical Society., 1995., p. 5 –shown -0.27/-0.08 (calculated) [3] ILO-WHO International Chemical Safety Cards (ICSCs) - pKa
- pKa = 10.87 (conjugate acid)[6]
2 values
Only one source reports it.
Value As written Source –shown pKa = 10.87 (conjugate acid) [6] Hazardous Substances Data Bank (HSDB)cites Perrin DD; Dissociation constants of organic bases in aqueous solution. IUPAC Chem Data Ser, Buttersworth, London (1965) – 5.6X10-4 at 25 °C [6] Hazardous Substances Data Bank (HSDB)cites Flick, E.W. Industrial Solvents Handbook. 3rd ed. Park Ridge, NJ: Noyes Publications, 1985., p. 525 - Vapor pressure
- 400 [mmHg] @20 °C[7]
5 values
3 of 4 sources agree on it (most common value).
Value As written Source 400 mmHg 400 mmHg at 68 °F (NTP, 1992) [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina. 1048 mmHg 1,048 mm Hg at 25 °C [6] Hazardous Substances Data Bank (HSDB)cites Daubert TE, Danner R; Physical and Thermodynamic Properties of Pure Chemicals Data Compilation. Washington, DC: Taylor and Francis (1995) 910 mmHg Vapor pressure, kPa at 20 °C: 121 [3] ILO-WHO International Chemical Safety Cards (ICSCs) 400 mmHg Vapor pressure, kPa at 2 °C: 53.3 [3] ILO-WHO International Chemical Safety Cards (ICSCs) 400 mmHgshown 400 [mm Hg] @20 °C [7] PAC Chemical Database, U.S. Department of Energy 2 more values were reported but failed the checks (unreadable or out of range), so they are not shown.
- Flash point
- -17 °C c.c.[3]
8 values
3 of 4 sources agree on it (most common value).
Value As written Source < −18 °C less than 0 °F (NTP, 1992) [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina. < −18 °C less than 0 °F (NFPA, 2010) [1] CAMEO Chemicalscites National Fire Protection Association. 2010. Fire Protection Guide to Hazardous Materials, 14th edition, edited by Guy R. Colonna. Quincy, MA: National Fire Protection Association. Note that this information is subject to the copyright restrictions of the organization that provided the data. −37.0 °C -36.99 °C (-34.58 °F) - closed cup [6] Hazardous Substances Data Bank (HSDB)cites Sigma-Aldrich; Material Safety Data Sheet for Ethylamine. Product Number: 724033, Version 4.7 (Revision Date 03/07/2015). Available from, as of March 13, 2015: https://www.sigmaaldrich.com/safety-center.html < −18 °C < 0 °F (<-18 °C) (open cup) [6] Hazardous Substances Data Bank (HSDB)cites National Fire Protection Association; Fire Protection Guide to Hazardous Materials. 14TH Edition, Quincy, MA 2010, p. 325-58 −17 °Cshown -17 °C c.c. [3] ILO-WHO International Chemical Safety Cards (ICSCs) −18 °C -18 °C c.c. [3] ILO-WHO International Chemical Safety Cards (ICSCs) −17 °C 1 °F [4] Occupational Safety and Health Administration (OSHA) −17 °C 1 °F [5] The National Institute for Occupational Safety and Health (NIOSH) - Autoignition temperature
- 385 °C[3]
4 values
3 of 3 sources agree on it (most common value).
Value As written Source 384 °C 724 °F (USCG, 1999) [1] CAMEO Chemicalscites U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office. 385 °C 725 °F (385 °C) [6] Hazardous Substances Data Bank (HSDB)cites National Fire Protection Association; Fire Protection Guide to Hazardous Materials. 14TH Edition, Quincy, MA 2010, p. 325-58 385 °Cshown 385 °C [3] ILO-WHO International Chemical Safety Cards (ICSCs) 385 °C 385 °C [3] ILO-WHO International Chemical Safety Cards (ICSCs)
Each value as its source reports it, with the source's number after it (listed under References). Where several sources report a property, the row shows the value most of them agree on, the rule the app uses; open the values to see every one.
Calculated
- Heavy atoms
- 3
- Rings
- 0
- Aromatic rings
- 0
- Fraction sp³ carbons (Fsp3)
- 1
- H-bond donors
- 1
- H-bond acceptors
- 1
- Rotatable bonds
- 0
- TPSA (Ų)
- 26
- Formal charge
- 0
- XLogP3
- -0.3 PubChem
- Complexity
- 2 PubChem
- Stereocenters
- None
- Double-bond geometry
- None specified
- Point group
- C1 of one 3D conformer with its hydrogens, by Athanor’s engine (as in the app)
Elemental analysis
- C53.28%
- H15.65%
- N31.07%
Isotope pattern
Each peak is a nominal mass with its abundance-weighted exact mass, as a percentage of the tallest, from IUPAC natural isotope abundances.
Computed from the structure with RDKit 2026.09 when this page was built, beside PubChem's own computed values from its record; where the two differ, both are shown.
Predicted
- log P
- -0.03 Crippen (Wildman and Crippen 1999)
- log S (water solubility)
- -0.1 ESOL (Delaney 2004), log mol/L
- Synthetic accessibility
- 2.17 SA score, 1 easy to 10 hard (Ertl and Schuffenhauer 2009)
Drug-likeness: Lipinski’s rule of five
- Molecular weight ≤ 500: 45.08
- log P ≤ 5 (Crippen): -0.03
- H-bond donors ≤ 5: 1
- H-bond acceptors ≤ 10: 1
Passes all four rules.
¹³C NMR shifts, predicted
Predictions, not measurements; each names its method. A measured log P, where a source reports one, is under Physical properties.
Safety
Danger
Harmonized EU classification (CLP Annex VI). Source [8].
Flammable
Compressed gas
Harmful or irritant
- H220Extremely flammable gas
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements: P203, P210, P222, P261, P264+P265, P271, P280, P304+P340, P305+P351+P338, P319, P337+P317, P377, P381, P403, P403+P233, P405, P501
View all classifications (3)
- [8] Regulation (EC) No 1272/2008 of the European Parliament and of the Council · DangerH220, H319, H335
- [9] European Chemicals Agency (ECHA) · 1,808 reports · DangerH220, H280, H302, H311, H314, H318, H319, H332, H335
- [6] Hazardous Substances Data Bank (HSDB) · DangerH220, H280, H319, H332, H335
Exposure limits
First aid
- Eyes: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. Immediately transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. Skin: Caution: Exposure of skin to compressed gases may result in freezing of the skin. Treatment for frostbite may be necessary.[1]
- Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]: Refer to the "General First Aid" section. Specific First Aid: For corrosives, in case of contact, immediately flush skin or eyes with running water for at least 30 minutes. Additional flushing may be required. In case of burns, immediately cool affected skin for as long as possible with cold water. Do not remove clothing if adhering to skin. (ERG, 2024)[1]
- General First Aid: · Call 911 or emergency medical service. · Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination. · Move victim to fresh air if it can be done safely. · Administer oxygen if breathing is difficult. · If victim is not breathing: -- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance. -- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped…[10]
- General First Aid: · Call 911 or emergency medical service. · Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination. · Move victim to fresh air if it can be done safely. · Administer oxygen if breathing is difficult. · If victim is not breathing: -- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance. -- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped…[10]
Storage
- Fireproof. Cool.[3]
- Fireproof. Cool. Well closed. Separated from acids and oxidants.[3]
- Conditions for safe storage, including any incompatibilities: Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): Gases[6]
- Ethylamine must be stored to avoid contact with strong acids (such as hydrochloric, sulfuric and nitric), or strong oxidizers (such as chlorine and bromine) because violent reactions occur. Store in tightly closed containers in a cool, well-ventilated area away from heat. Sources of ignition such as smoking and open flames are prohibited where methylamine is handled, used, or stored. Metal containers involving the transfer of 5 gallons or more of ethylamine should be grounded and bonded. Drums must be equipped with self-closing valves, pressure vacuum bungs, and flame arresters.[6]
Incompatibilities
- Incompatible materials: Strong oxidizing agents, nickel, copper, strong acids, zinc. Ethylamine, anhydrous is packaged in steel cylinders. Cool to 0 °C before opening. Incompatible with silver, mercury and brass.[6]
- The aqueous solution is a strong base. Forms explosive mixture with air. Reacts violently with strong acids, strong oxidizers, cellulose nitrate, and organic compounds causing fire and explosion hazard. Also incompatible with organic anhydrides, isocyanates, vinyl acetate, acrylates, substituted allyls, alkylene oxides, epichlorohydrin, ketones, aldehydes, alcohols, glycols, phenols, cresols, caprolactum solution. Attacks nonferrous metals: Aluminum, copper, lead, tin, zinc and alloys, some plastics, rubber and coatings.[6]
- Incompatible with cellulose nitrate or oxidizers.[6]
- Strong acids; strong oxidizers; copper, tin and zinc in presense of moisture; cellulose nitrate; chlorine; hypochlorites.[6]
Always read the supplier’s safety data sheet before working with it.
Spectra
- NMRHazardous Substances Data Bank (HSDB) · NMRShiftDB
- 1H NMRSpectraBase (Varian A-60)
- 13C NMRHazardous Substances Data Bank (HSDB) · Human Metabolome Database (HMDB) (Varian · 25.16 MHz · CDCl3) · SpectraBase
- 15N NMRSpectraBase
- GC-MSNIST Mass Spectrometry Data Center · NIST Mass Spectrometry Data Center · SpectraBase (GC/MS)
- MS-MSHuman Metabolome Database (HMDB) (LC-ESI-QQ · positive) · Human Metabolome Database (HMDB) (LC-ESI-QQ · positive) · Human Metabolome Database (HMDB) (LC-ESI-QQ · positive) · Human Metabolome Database (HMDB) (LC-ESI-QQ · positive) · Human Metabolome Database (HMDB) (LC-ESI-QQ · positive)
- LC-MSMassBank Europe (API3000, Applied Biosystems · LC-ESI-QQ · POSITIVE) · MassBank Europe (API3000, Applied Biosystems · LC-ESI-QQ · POSITIVE) · MassBank Europe (API3000, Applied Biosystems · LC-ESI-QQ · POSITIVE) · MassBank Europe (API3000, Applied Biosystems · LC-ESI-QQ · POSITIVE) · MassBank Europe (API3000, Applied Biosystems · LC-ESI-QQ · POSITIVE) · MassBank of North America (MoNA) (API3000, Applied Biosystems · LC-ESI-QQ · positive)
- Other MSHazardous Substances Data Bank (HSDB)
- UVHazardous Substances Data Bank (HSDB)
- IRHazardous Substances Data Bank (HSDB)
- FTIRSpectraBase (Bruker IFS 85 · Cell)
- ATR-IRSpectraBase
- Vapor Phase IRSpectraBase (Vapor Phase)
- RamanSpectraBase
Experimental spectra held by these sources; each link opens the source's own record.
Literature
Reading PubChem, OpenAlex and GSRS…
Bioactivity
Reading ChEMBL…
References
- [1]CAMEO Chemicals · Public domain (NOAA) · via PubChem · retrieved 2026-10-14
- [2]EPA Chemical Data Reporting (CDR) · Public domain (US EPA) · via PubChem · retrieved 2026-10-14
- [3]ILO-WHO International Chemical Safety Cards (ICSCs) · CC BY 4.0 · via PubChem · retrieved 2026-10-14
- [4]Occupational Safety and Health Administration (OSHA) · Public domain (US DOL) · via PubChem · retrieved 2026-10-14
- [5]The National Institute for Occupational Safety and Health (NIOSH) · Public domain (US CDC) · via PubChem · retrieved 2026-10-14
- [6]Hazardous Substances Data Bank (HSDB) · Public domain (US NLM) · via PubChem · retrieved 2026-10-14
- [7]PAC Chemical Database, U.S. Department of Energy · Public domain (US DOE) · via PubChem · retrieved 2026-10-14
- [8]Regulation (EC) No 1272/2008 of the European Parliament and of the Council · EU reuse policy, CC BY 4.0 · via PubChem · retrieved 2026-10-14
- [9]European Chemicals Agency (ECHA) · ECHA legal notice: reuse with acknowledgement · via PubChem · retrieved 2026-10-14
- [10]Emergency Response Guidebook (ERG) · Public domain (US DOT) · via PubChem · retrieved 2026-10-14
- [11]NMRShiftDB · Linked only · via PubChem · retrieved 2026-10-14
- [12]SpectraBase · Linked only · via PubChem · retrieved 2026-10-14
- [13]Human Metabolome Database (HMDB) · Linked only · via PubChem · retrieved 2026-10-14
- [14]NIST Mass Spectrometry Data Center · Linked only · via PubChem · retrieved 2026-10-14
- [15]MassBank Europe · Linked only · via PubChem · retrieved 2026-10-14
- [16]MassBank of North America (MoNA) · CC BY 4.0 · via PubChem · retrieved 2026-10-14
- ·Calculated values: computed by Athanor with RDKit 2026.09 from the structure.
- ·Literature on PubChem
Data last updated 2026-10-14.
