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Ethylamine

Athanor · official

C2H7N · 45.08 g/mol

IUPAC name: ethanamine

Also called aminoethane

Open in Athanor
The structure of Ethylamine
Drawn from its SMILES with RDKit430
FlammableCompressed gasHarmful or irritantDangerExtremely flammable gas · Causes serious eye irritation · May cause respiratory irritation

Names and identifiers

IUPAC name
ethanamine
Synonyms
aminoethane, Ethanamine, Aminoethane
+ 36 more

Monoethylamine, 1-Aminoethane, Aethylamine, Etilamina, Etyloamina, YG6MGA6AT5, AI3-24228, DTXSID8025678, FEMA NO. 4236, CHEBI:15862, Ethylamine (anhydrous), RefChem:5816, DTXCID005678, 200-834-7, Ethyl amine, 1,1,2,2,2-pentadeuterioethanamine, MFCD00008160, Ethylamine Solution (2.0 M in MeOH), C2H5NH2, Ethylamin, ethane, amino-, Ethylamine, 97%, Ethylamine Solution (2.0 M in THF), Etilamina [Italian], Etyloamina [Polish], Ethamine, Aethylamine [German], Ethylamine (50-70% in aqueous solution), CCRIS 6261, HSDB 803, EINECS 200-834-7, UNII-YG6MGA6AT5, UN1036, UN2270, ethaneamine, ethyamine

Molecular formula
C2H7N
Empirical formula
C2H7N
Molecular weight
45.08 g/mol
Exact mass
45.05785
CAS number
75-04-7
PubChem CID
6341
Canonical SMILES
CCN
Isomeric SMILES
CCN
InChI
InChI=1S/C2H7N/c1-2-3/h2-3H2,1H3
InChIKey
QUSNBJAOOMFDIB-UHFFFAOYSA-N
Molfile

Names, InChI and the identifiers from PubChem, retrieved 2026-10-14.

Physical properties

TemperaturePressureDensity
Appearance
Colorless gas or water-white liquid (below 62 degrees F) [Shipped as a liquefied compressed gas][6]
8 values

From Hazardous Substances Data Bank (HSDB), the most authoritative source here.

ValueAs writtenSource
–Ethylamine appears as a colorless liquid or a gas (boiling point 62 °F) with an odor of ammonia. Flash point less than 0 °F. Density of liquid 5.7 lb / gal. Corrosive to the skin and eyes. Vapors are heavier than air. Produces toxic oxides of nitrogen during combustion. Exposure of the closed container to intense heat may cause it to rupture violently and rocket.[1] CAMEO Chemicals
–Ethylamine, aqueous solution, with not less than 50% but not more than 70% ethylamine appears as an aqueous solution of a gas. Odor ranges from fishlike to ammonia-like as the vapor concentration increases. Corrosive to skin and eyes. Less dense than water. Vapors are heavier than air. Produces toxic oxides of nitrogen during combustion.[1] CAMEO Chemicals
–Gas Vapor; Liquid[2] EPA Chemical Data Reporting (CDR)
–COLOURLESS COMPRESSED LIQUEFIED GAS WITH PUNGENT ODOUR.[3] ILO-WHO International Chemical Safety Cards (ICSCs)
–COLOURLESS SOLUTION IN WATER WITH PUNGENT ODOUR.[3] ILO-WHO International Chemical Safety Cards (ICSCs)
–Colorless gas or water-white liquid (below 62 °F) with an ammonia-like odor.[4] Occupational Safety and Health Administration (OSHA)
–Colorless gas or water-white liquid (below 62 °F) with an ammonia-like odor. [Note: Shipped as a liquefied compressed gas.][5] The National Institute for Occupational Safety and Health (NIOSH)
–shownColorless gas or water-white liquid (below 62 degrees F) [Shipped as a liquefied compressed gas][6] Hazardous Substances Data Bank (HSDB)cites NIOSH. NIOSH Pocket Guide to Chemical Hazards. Department of Health & Human Services, Centers for Disease Control & Prevention. National Institute for Occupational Safety & Health. DHHS (NIOSH) Publication No. 2010-168 (2010). Available from: https://www.cdc.gov/niosh/npg
Melting point
-80.6 °C[7]
6 values

5 of 5 sources agree on it (most common value).

ValueAs writtenSource
−81 °C-114 °F (NTP, 1992)[1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
−81 °C-81 °C[3] ILO-WHO International Chemical Safety Cards (ICSCs)
−81 °C-81 °C[3] ILO-WHO International Chemical Safety Cards (ICSCs)
−81 °C-114 °F[4] Occupational Safety and Health Administration (OSHA)
−80.6 °Cshown-80.6 °C[7] PAC Chemical Database, U.S. Department of Energy
−81 °C-114 °F[5] The National Institute for Occupational Safety and Health (NIOSH)
Boiling point
16.6 °C[3]
6 values

5 of 5 sources agree on it (most common value).

ValueAs writtenSource
16.6 °C61.9 °F at 760 mmHg (NTP, 1992)[1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
16.6 °Cshown16.6 °C[3] ILO-WHO International Chemical Safety Cards (ICSCs)
17 °C17 °C[3] ILO-WHO International Chemical Safety Cards (ICSCs)
17 °C62 °F[4] Occupational Safety and Health Administration (OSHA)
16.6 °C16.6 °C @760 [mm Hg][7] PAC Chemical Database, U.S. Department of Energy
17 °C62 °F[5] The National Institute for Occupational Safety and Health (NIOSH)
Density
0.687 at 15 °C (59 °F) (USCG, 1999) - Less dense than water[1]
7 values

4 of 5 sources agree on it (most common value).

ValueAs writtenSource
–shown0.687 at 59 °F (USCG, 1999) - Less dense than water[1] CAMEO Chemicalscites U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office.
–Relative density (water = 1): 0.7 (liquid)[3] ILO-WHO International Chemical Safety Cards (ICSCs)
–Relative density (water = 1): 0.81[3] ILO-WHO International Chemical Safety Cards (ICSCs)
–0.69 (liquid)[4] Occupational Safety and Health Administration (OSHA)
–0.662 @ 20°C[7] PAC Chemical Database, U.S. Department of Energy
–0.69 (Liquid)[5] The National Institute for Occupational Safety and Health (NIOSH)
–1.61(relative gas density)[5] The National Institute for Occupational Safety and Health (NIOSH)
Solubility in water
Solubility in water: miscible[3]
3 values

From ILO-WHO International Chemical Safety Cards (ICSCs), the most authoritative source here.

ValueAs writtenSource
–Very soluble (NTP, 1992)[1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
–shownSolubility in water: miscible[3] ILO-WHO International Chemical Safety Cards (ICSCs)
–Miscible[5] The National Institute for Occupational Safety and Health (NIOSH)
log P
-0.27/-0.08 (calculated)[3]
2 values

Sources disagree; from ILO-WHO International Chemical Safety Cards (ICSCs), the most authoritative.

ValueAs writtenSource
–log Kow = -0.13[6] Hazardous Substances Data Bank (HSDB)cites Hansch, C., Leo, A., D. Hoekman. Exploring QSAR - Hydrophobic, Electronic, and Steric Constants. Washington, DC: American Chemical Society., 1995., p. 5
–shown-0.27/-0.08 (calculated)[3] ILO-WHO International Chemical Safety Cards (ICSCs)
pKa
pKa = 10.87 (conjugate acid)[6]
2 values

Only one source reports it.

ValueAs writtenSource
–shownpKa = 10.87 (conjugate acid)[6] Hazardous Substances Data Bank (HSDB)cites Perrin DD; Dissociation constants of organic bases in aqueous solution. IUPAC Chem Data Ser, Buttersworth, London (1965)
–5.6X10-4 at 25 °C[6] Hazardous Substances Data Bank (HSDB)cites Flick, E.W. Industrial Solvents Handbook. 3rd ed. Park Ridge, NJ: Noyes Publications, 1985., p. 525
Vapor pressure
400 [mmHg] @20 °C[7]
5 values

3 of 4 sources agree on it (most common value).

ValueAs writtenSource
400 mmHg400 mmHg at 68 °F (NTP, 1992)[1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
1048 mmHg1,048 mm Hg at 25 °C[6] Hazardous Substances Data Bank (HSDB)cites Daubert TE, Danner R; Physical and Thermodynamic Properties of Pure Chemicals Data Compilation. Washington, DC: Taylor and Francis (1995)
910 mmHgVapor pressure, kPa at 20 °C: 121[3] ILO-WHO International Chemical Safety Cards (ICSCs)
400 mmHgVapor pressure, kPa at 2 °C: 53.3[3] ILO-WHO International Chemical Safety Cards (ICSCs)
400 mmHgshown400 [mm Hg] @20 °C[7] PAC Chemical Database, U.S. Department of Energy

2 more values were reported but failed the checks (unreadable or out of range), so they are not shown.

Flash point
-17 °C c.c.[3]
8 values

3 of 4 sources agree on it (most common value).

ValueAs writtenSource
< −18 °Cless than 0 °F (NTP, 1992)[1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
< −18 °Cless than 0 °F (NFPA, 2010)[1] CAMEO Chemicalscites National Fire Protection Association. 2010. Fire Protection Guide to Hazardous Materials, 14th edition, edited by Guy R. Colonna. Quincy, MA: National Fire Protection Association. Note that this information is subject to the copyright restrictions of the organization that provided the data.
−37.0 °C-36.99 °C (-34.58 °F) - closed cup[6] Hazardous Substances Data Bank (HSDB)cites Sigma-Aldrich; Material Safety Data Sheet for Ethylamine. Product Number: 724033, Version 4.7 (Revision Date 03/07/2015). Available from, as of March 13, 2015: https://www.sigmaaldrich.com/safety-center.html
< −18 °C< 0 °F (<-18 °C) (open cup)[6] Hazardous Substances Data Bank (HSDB)cites National Fire Protection Association; Fire Protection Guide to Hazardous Materials. 14TH Edition, Quincy, MA 2010, p. 325-58
−17 °Cshown-17 °C c.c.[3] ILO-WHO International Chemical Safety Cards (ICSCs)
−18 °C-18 °C c.c.[3] ILO-WHO International Chemical Safety Cards (ICSCs)
−17 °C1 °F[4] Occupational Safety and Health Administration (OSHA)
−17 °C1 °F[5] The National Institute for Occupational Safety and Health (NIOSH)
Autoignition temperature
385 °C[3]
4 values

3 of 3 sources agree on it (most common value).

ValueAs writtenSource
384 °C724 °F (USCG, 1999)[1] CAMEO Chemicalscites U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office.
385 °C725 °F (385 °C)[6] Hazardous Substances Data Bank (HSDB)cites National Fire Protection Association; Fire Protection Guide to Hazardous Materials. 14TH Edition, Quincy, MA 2010, p. 325-58
385 °Cshown385 °C[3] ILO-WHO International Chemical Safety Cards (ICSCs)
385 °C385 °C[3] ILO-WHO International Chemical Safety Cards (ICSCs)

Each value as its source reports it, with the source's number after it (listed under References). Where several sources report a property, the row shows the value most of them agree on, the rule the app uses; open the values to see every one.

Calculated

Heavy atoms
3
Rings
0
Aromatic rings
0
Fraction sp³ carbons (Fsp3)
1
H-bond donors
1
H-bond acceptors
1
Rotatable bonds
0
TPSA (Ų)
26
Formal charge
0
XLogP3
-0.3 PubChem
Complexity
2 PubChem
Stereocenters
None
Double-bond geometry
None specified
Point group
C1 of one 3D conformer with its hydrogens, by Athanor’s engine (as in the app)

Elemental analysis

  • C53.28%
  • H15.65%
  • N31.07%

Isotope pattern

100%45.0582.6%46.060

Each peak is a nominal mass with its abundance-weighted exact mass, as a percentage of the tallest, from IUPAC natural isotope abundances.

Computed from the structure with RDKit 2026.09 when this page was built, beside PubChem's own computed values from its record; where the two differ, both are shown.

Predicted

log P
-0.03 Crippen (Wildman and Crippen 1999)
log S (water solubility)
-0.1 ESOL (Delaney 2004), log mol/L
Synthetic accessibility
2.17 SA score, 1 easy to 10 hard (Ertl and Schuffenhauer 2009)

Drug-likeness: Lipinski’s rule of five

  • Molecular weight ≤ 500: 45.08
  • log P ≤ 5 (Crippen): -0.03
  • H-bond donors ≤ 5: 1
  • H-bond acceptors ≤ 10: 1

Passes all four rules.

¹³C NMR shifts, predicted

Predictions, not measurements; each names its method. A measured log P, where a source reports one, is under Physical properties.

Safety

Danger

Harmonized EU classification (CLP Annex VI). Source [8].

  • Flammable
  • Compressed gas
  • Harmful or irritant
430
NFPA 704[6]
  • H220Extremely flammable gas
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements: P203, P210, P222, P261, P264+P265, P271, P280, P304+P340, P305+P351+P338, P319, P337+P317, P377, P381, P403, P403+P233, P405, P501

View all classifications (3)
  • [8] Regulation (EC) No 1272/2008 of the European Parliament and of the Council · DangerH220, H319, H335
  • [9] European Chemicals Agency (ECHA) · 1,808 reports · DangerH220, H280, H302, H311, H314, H318, H319, H332, H335
  • [6] Hazardous Substances Data Bank (HSDB) · DangerH220, H280, H319, H332, H335

Exposure limits

  • PEL-TWA (8-Hour Time Weighted Average): 10 ppm (18 mg/m³)[4]
  • PEL: TWA 10 ppm (18 mg/m3)[5]
  • TLV: 5 ppm as TWA; 15 ppm as STEL; (skin).[3]
  • TLV-TWA (Time Weighted Average): 5 ppm [2012][4]
  • TLV-STEL (Short Term Exposure Limit): 15 ppm [2012][4]
  • IDLH: 600 ppm (NIOSH, 2024)[1]

First aid

  • Eyes: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. Immediately transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. Skin: Caution: Exposure of skin to compressed gases may result in freezing of the skin. Treatment for frostbite may be necessary.[1]
  • Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]: Refer to the "General First Aid" section. Specific First Aid: For corrosives, in case of contact, immediately flush skin or eyes with running water for at least 30 minutes. Additional flushing may be required. In case of burns, immediately cool affected skin for as long as possible with cold water. Do not remove clothing if adhering to skin. (ERG, 2024)[1]
  • General First Aid: · Call 911 or emergency medical service. · Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination. · Move victim to fresh air if it can be done safely. · Administer oxygen if breathing is difficult. · If victim is not breathing: -- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance. -- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped…[10]
  • General First Aid: · Call 911 or emergency medical service. · Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination. · Move victim to fresh air if it can be done safely. · Administer oxygen if breathing is difficult. · If victim is not breathing: -- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance. -- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped…[10]

Storage

  • Fireproof. Cool.[3]
  • Fireproof. Cool. Well closed. Separated from acids and oxidants.[3]
  • Conditions for safe storage, including any incompatibilities: Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): Gases[6]
  • Ethylamine must be stored to avoid contact with strong acids (such as hydrochloric, sulfuric and nitric), or strong oxidizers (such as chlorine and bromine) because violent reactions occur. Store in tightly closed containers in a cool, well-ventilated area away from heat. Sources of ignition such as smoking and open flames are prohibited where methylamine is handled, used, or stored. Metal containers involving the transfer of 5 gallons or more of ethylamine should be grounded and bonded. Drums must be equipped with self-closing valves, pressure vacuum bungs, and flame arresters.[6]

Incompatibilities

  • Incompatible materials: Strong oxidizing agents, nickel, copper, strong acids, zinc. Ethylamine, anhydrous is packaged in steel cylinders. Cool to 0 °C before opening. Incompatible with silver, mercury and brass.[6]
  • The aqueous solution is a strong base. Forms explosive mixture with air. Reacts violently with strong acids, strong oxidizers, cellulose nitrate, and organic compounds causing fire and explosion hazard. Also incompatible with organic anhydrides, isocyanates, vinyl acetate, acrylates, substituted allyls, alkylene oxides, epichlorohydrin, ketones, aldehydes, alcohols, glycols, phenols, cresols, caprolactum solution. Attacks nonferrous metals: Aluminum, copper, lead, tin, zinc and alloys, some plastics, rubber and coatings.[6]
  • Incompatible with cellulose nitrate or oxidizers.[6]
  • Strong acids; strong oxidizers; copper, tin and zinc in presense of moisture; cellulose nitrate; chlorine; hypochlorites.[6]

Always read the supplier’s safety data sheet before working with it.

Spectra

Experimental spectra held by these sources; each link opens the source's own record.

Literature

Reading PubChem, OpenAlex and GSRS…

Bioactivity

Reading ChEMBL…

References

  1. [1]CAMEO Chemicals · Public domain (NOAA) · via PubChem · retrieved 2026-10-14
  2. [2]EPA Chemical Data Reporting (CDR) · Public domain (US EPA) · via PubChem · retrieved 2026-10-14
  3. [3]ILO-WHO International Chemical Safety Cards (ICSCs) · CC BY 4.0 · via PubChem · retrieved 2026-10-14
  4. [4]Occupational Safety and Health Administration (OSHA) · Public domain (US DOL) · via PubChem · retrieved 2026-10-14
  5. [5]The National Institute for Occupational Safety and Health (NIOSH) · Public domain (US CDC) · via PubChem · retrieved 2026-10-14
  6. [6]Hazardous Substances Data Bank (HSDB) · Public domain (US NLM) · via PubChem · retrieved 2026-10-14
  7. [7]PAC Chemical Database, U.S. Department of Energy · Public domain (US DOE) · via PubChem · retrieved 2026-10-14
  8. [8]Regulation (EC) No 1272/2008 of the European Parliament and of the Council · EU reuse policy, CC BY 4.0 · via PubChem · retrieved 2026-10-14
  9. [9]European Chemicals Agency (ECHA) · ECHA legal notice: reuse with acknowledgement · via PubChem · retrieved 2026-10-14
  10. [10]Emergency Response Guidebook (ERG) · Public domain (US DOT) · via PubChem · retrieved 2026-10-14
  11. [11]NMRShiftDB · Linked only · via PubChem · retrieved 2026-10-14
  12. [12]SpectraBase · Linked only · via PubChem · retrieved 2026-10-14
  13. [13]Human Metabolome Database (HMDB) · Linked only · via PubChem · retrieved 2026-10-14
  14. [14]NIST Mass Spectrometry Data Center · Linked only · via PubChem · retrieved 2026-10-14
  15. [15]MassBank Europe · Linked only · via PubChem · retrieved 2026-10-14
  16. [16]MassBank of North America (MoNA) · CC BY 4.0 · via PubChem · retrieved 2026-10-14
  17. ·Calculated values: computed by Athanor with RDKit 2026.09 from the structure.
  18. ·Literature on PubChem

Data last updated 2026-10-14.