Bisacrylamide

Athanor · official

C₇H₁₀N₂O₂ · 154.17 g/mol

IUPAC name: N-[(prop-2-enoylamino)methyl]prop-2-enamide

Also called N,N'-methylenebisacrylamide, bis, crosslinker

Reagents

Open in Athanor

Drawn from its SMILES with RDKit

DangerMay cause genetic defects

Names and identifiers

IUPAC name: N-[(prop-2-enoylamino)methyl]prop-2-enamide
Synonyms: N,N'-methylenebisacrylamide, bis, crosslinker
+ 37 more
N,N'-METHYLENEBISACRYLAMIDE, Methylenebisacrylamide, Methylenediacrylamide, N,N'-Methylenebis(acrylamide), 2-Propenamide, N,N'-methylenebis-, N,N'-Methylidenebisacrylamide, Acrylamide, N,N'-methylenebis-, N,N'-Methylenebis(2-propenamide), DTXSID8025595, EDK4RIE19C, DTXCID205595, N,N'-Methylenebis[acrylamide], RefChem:161037, n,n'-methylene-bis(acrylamide), 2-propenamide, N,N'-methyl-enebis, N,N'-METHYLENEBIS-2-PROPENAMIDE, methylene bisacrylamide, N,N'-Methylenediacrylamide, n,n-methylenebisacrylamide, N,N'-Methylene-bis-acrylamide, Bis-acrylamide, N-[(prop-2-enoylamino)methyl]prop-2-enamide, MBAA, N-[(prop-2-enamido)methyl]prop-2-enamide, NSC 406836, MFCD00008625, MLS001055454, NSC-406836, Bisacrylamide; MBA;Methylenebisacrylamide, NCGC00090721-03, SMR001227199, Acrylamide,N'-methylenebis-, 2-Propenamide,N'-methylenebis-, N,N inverted exclamation marka-Methylenebis(acrylamide), bis acrylamide, CCRIS 4672, N,N'-METHYLENE-bis-ACRYLAMIDE,ULTRA PURE
Molecular formula: C₇H₁₀N₂O₂
Empirical formula: C₇H₁₀N₂O₂
Molecular weight: 154.17 g/mol
Exact mass: 154.07423
CAS number: 110-26-9
PubChem CID: 8041
Canonical SMILES: C=CC(=O)NCNC(=O)C=C
Isomeric SMILES: C=CC(=O)NCNC(=O)C=C
InChI: InChI=1S/C7H10N2O2/c1-3-6(10)8-5-9-7(11)4-2/h3-4H,1-2,5H2,(H,8,10)(H,9,11)
InChIKey: ZIUHHBKFKCYYJD-UHFFFAOYSA-N
Molfile

Names, InChI and the identifiers from PubChem, retrieved 2026-10-14.

Physical properties

TemperaturePressureDensity

Appearance: N,n'-methylenebisacrylamide is a white crystalline powder with a neutral odor. (NTP, 1992)[1]
2 values
From CAMEO Chemicals, the most authoritative source here.
Value As written Source
–shown N,n'-methylenebisacrylamide is a white crystalline powder with a neutral odor. (NTP, 1992) [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
– Dry Powder [2] EPA Chemical Data Reporting (CDR)
Melting point: 185 °C (365 °F) (with decomposition) (NTP, 1992)[1]
Density: 1.235 @ 30°C[3]
2 values
2 of 2 sources agree on it (most common value).
Value As written Source
– 1.235 at 86 °F (NTP, 1992) - Denser than water [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
–shown 1.235 @ 30°C [3] PAC Chemical Database, U.S. Department of Energy
Solubility in water: 0.1 to 1 mg/mL at 18 °C (64 °F, NTP 1992)[1]

Value	As written	Source
–shown	N,n'-methylenebisacrylamide is a white crystalline powder with a neutral odor. (NTP, 1992)	[1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
–	Dry Powder	[2] EPA Chemical Data Reporting (CDR)

Value	As written	Source
–	1.235 at 86 °F (NTP, 1992) - Denser than water	[1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
–shown	1.235 @ 30°C	[3] PAC Chemical Database, U.S. Department of Energy

Each value as its source reports it, with the source's number after it (listed under References). Where several sources report a property, the row shows the value most of them agree on, the rule the app uses; open the values to see every one.

Calculated

Heavy atoms: 11
Rings: 0
Aromatic rings: 0
Fraction sp³ carbons (Fsp3): 0.14
H-bond donors: 2
H-bond acceptors: 2
Rotatable bonds: 4
TPSA (Å²): 58.2
Formal charge: 0
XLogP3: 0.1 PubChem
Complexity: 167 PubChem
Stereocenters: None
Double-bond geometry: None specified
Point group: C1 of one 3D conformer with its hydrogens, by Athanor’s engine (as in the app)

Elemental analysis

C54.54%
H6.54%
N18.17%
O20.76%

Isotope pattern

Each peak is a nominal mass with its abundance-weighted exact mass, as a percentage of the tallest, from IUPAC natural isotope abundances.

Computed from the structure with RDKit 2026.09 when this page was built, beside PubChem's own computed values from its record; where the two differ, both are shown.

Predicted

log P: -0.45 Crippen (Wildman and Crippen 1999)
log S (water solubility): -0.25 ESOL (Delaney 2004), log mol/L
Synthetic accessibility: 3 SA score, 1 easy to 10 hard (Ertl and Schuffenhauer 2009)

Drug-likeness: Lipinski’s rule of five

Molecular weight ≤ 500: 154.17
log P ≤ 5 (Crippen): -0.45
H-bond donors ≤ 5: 2
H-bond acceptors ≤ 10: 2

Passes all four rules.

¹³C NMR shifts, predicted

Predictions, not measurements; each names its method. A measured log P, where a source reports one, is under Physical properties.

Safety

Danger

Harmonized EU classification (CLP Annex VI). Source [4].

Health hazard

H340May cause genetic defects

Precautionary statements: P203, P280, P318, P405, P501

View all classifications (2)

[4] Regulation (EC) No 1272/2008 of the European Parliament and of the Council · DangerH340
[5] European Chemicals Agency (ECHA) · 544 reports · DangerH301, H302, H312, H317, H318, H332, H340, H350, H351, H360, H361, H372

First aid

Eyes: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. Immediately transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. Skin: Immediately flood affected skin with water while removing and isolating all contaminated clothing.[1]

Safety data sheets on the supplier’s page: Thermo Fisher Scientific, Sigma-Aldrich, ChemDiv.

Always read the supplier’s safety data sheet before working with it.

Spectra

Experimental spectra held by these sources; each link opens the source's own record.

Literature

Reading PubChem, OpenAlex and GSRS…

Bioactivity

Reading ChEMBL…

References

[1]CAMEO Chemicals · Public domain (NOAA) · via PubChem · retrieved 2026-10-14
[2]EPA Chemical Data Reporting (CDR) · Public domain (US EPA) · via PubChem · retrieved 2026-10-14
[3]PAC Chemical Database, U.S. Department of Energy · Public domain (US DOE) · via PubChem · retrieved 2026-10-14
[4]Regulation (EC) No 1272/2008 of the European Parliament and of the Council · EU reuse policy, CC BY 4.0 · via PubChem · retrieved 2026-10-14
[5]European Chemicals Agency (ECHA) · ECHA legal notice: reuse with acknowledgement · via PubChem · retrieved 2026-10-14
[6]SpectraBase · Linked only · via PubChem · retrieved 2026-10-14
[7]NIST Mass Spectrometry Data Center · Linked only · via PubChem · retrieved 2026-10-14
[8]MassBank Europe · Linked only · via PubChem · retrieved 2026-10-14
·Calculated values: computed by Athanor with RDKit 2026.09 from the structure.
·Literature on PubChem

Data last updated 2026-10-14.