Phenol

Athanor · official

C₆H₆O · 94.11 g/mol

Also called carbolic acid, hydroxybenzene

Reagents Rings

Open in Athanor

Drawn from its SMILES with RDKit

DangerToxic if swallowed · Toxic in contact with skin · Causes severe skin burns and eye damage · Toxic if inhaled · Suspected of causing genetic defects

Names and identifiers

IUPAC name: phenol
Synonyms: carbolic acid, hydroxybenzene, Hydroxybenzene
+ 36 more
Phenic acid, Oxybenzene, Benzenol, Phenylic acid, Phenylic alcohol, Monophenol, Phenyl hydrate, Phenyl hydroxide, PhOH, Monohydroxybenzene, Paoscle, Izal, Phenyl alcohol, Phenole, Phenol alcohol, Acide carbolique, Phenol, liquefied, Fenolo, Carbolsaure, Fenol, Liquid phenol, Liquefied phenol, Phenol, pure, Fenosmolin, Fenosmoline, Rcra waste number U188, Liquified Phenol, Phenol, molten, Carbolicum acidum, NCI-C50124, Baker's P & S liquid & Ointment, Baker's P and S Liquid and Ointment, Caswell No. 649, 2-allphenol, Phenol, liquified, DTXSID5021124
Molecular formula: C₆H₆O
Empirical formula: C₆H₆O
Molecular weight: 94.11 g/mol
Exact mass: 94.04186
CAS number: 108-95-2
PubChem CID: 996
Canonical SMILES: C1=CC=C(C=C1)O
Isomeric SMILES: C1=CC=C(C=C1)O
InChI: InChI=1S/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H
InChIKey: ISWSIDIOOBJBQZ-UHFFFAOYSA-N
Molfile

Names, InChI and the identifiers from PubChem, retrieved 2026-10-14.

Physical properties

TemperaturePressureDensity

Appearance: Colorless to light pink crystalline solid. [Note: Phenol liquefies by mixing with about 8% water.][6]
12 values
From Hazardous Substances Data Bank (HSDB), the most authoritative source here.
Value As written Source
– Phenol solution, [aqueous] is a white crystalline mass dissolved in an aqueous solution. Solution may be colorless to slightly pink in color with a distinctive phenol odor; sharp burning taste. Aqueous solution will be acidic and act as such. Toxic by ingestion, inhalation and skin absorption; strong irritant to tissues. [1] CAMEO Chemicals
– Phenol, liquid appears as a colorless liquid when pure, otherwise pink or red. Combustible. Flash point 175 °F. Must be heated before ignition may occur easily. Vapors are heavier than air. Corrosive to skin but because of anesthetic qualities will numb rather than burn. Upon contact skin may turn white. May be lethal by skin absorption. Does not react with water. Stable in normal transportation. Reactive with various chemicals and may be corrosive to lead, aluminum and its alloys, certain plastics, and rubber. Freezing point about 105 °F. Density 8.9 lb / gal. Used to make plastics, adhesives [1] CAMEO Chemicals
– Phenol, molten is the white crystalline solid shipped at an elevated temperature to form a semi-solid. It is very hot and may cause burns from contact and also may cause the ignition of combustible materials. It is toxic by ingestion, and inhalation of its fumes, and skin absorption. It may also be very irritating to skin and eyes. It is used to make other chemicals. [1] CAMEO Chemicals
– Phenol, solid appears as a solid melting at 110 °F. Colorless if pure, otherwise pink or red. Flash point 175 °F. Density 9.9 lb / gal. Vapors are heavier than air Corrosive to the skin (turning skin white) but because of its anesthetic quality numbs rather than burn. Lethal amounts can be absorbed through the skin. Used to make plastics and adhesives. [1] CAMEO Chemicals
– Dry Powder; Liquid; Large Crystals; Gas Vapor; Liquid; CBI [2] EPA Chemical Data Reporting (CDR)
– COLOURLESS-TO-YELLOW OR LIGHT PINK CRYSTALS WITH CHARACTERISTIC ODOUR. [3] ILO-WHO International Chemical Safety Cards (ICSCs)
– Colorless to light-pink, crystalline solid with a sweet, acrid odor. [4] Occupational Safety and Health Administration (OSHA)
– Colorless to light-pink, crystalline solid with a sweet, acrid odor. [Note: Phenol liquefies by mixing with about 8% water.] [5] The National Institute for Occupational Safety and Health (NIOSH)
– White crystalline mass of hygroscopic, translucent needle-shaped crystals; pink or red when impurities are present; darkens on exposure to light [6] Hazardous Substances Data Bank (HSDB)cites Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V3 383
– White, crystalline mass that turns pink or red if not perfectly pure or if under influence of light. [6] Hazardous Substances Data Bank (HSDB)cites Lewis, R.J., Sr (Ed.). Hawley's Condensed Chemical Dictionary. 13th ed. New York, NY: John Wiley & Sons, Inc. 1997., p. 860
– Colorless to light pink, interlaced, or separate, needleshaped crystals, or a ... light pink, crystalline mass [6] Hazardous Substances Data Bank (HSDB)cites Osol, A. (ed.). Remington's Pharmaceutical Sciences. 16th ed. Easton, Pennsylvania: Mack Publishing Co., 1980., p. 1262
–shown Colorless to light pink crystalline solid. [Note: Phenol liquefies by mixing with about 8% water.] [6] Hazardous Substances Data Bank (HSDB)cites NIOSH. NIOSH Pocket Guide to Chemical Hazards. DHHS (NIOSH) Publication No. 94-116. Washington, D.C.: U.S. Government Printing Office, June 1994., p. 248
Odor: Sweet, tarry odor[6]
2 values
From Hazardous Substances Data Bank (HSDB), the most authoritative source here.
Value As written Source
– Distinct aromatic, somewhat sickening sweet and acrid odor, discernable at 0.5 to 5 ppm [6] Hazardous Substances Data Bank (HSDB)cites Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V4 383
–shown Sweet, tarry odor [6] Hazardous Substances Data Bank (HSDB)cites Kirk-Othmer Encyclopedia of Chemical Technology. 4th ed. Volumes 1: New York, NY. John Wiley and Sons, 1991-Present., p. V18 (2001) 592
Melting point: 40.91 °C[6]
8 values
3 of 6 sources agree on it (most common value).
Value As written Source
43 °C 109 °F (NTP, 1992) [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
43 °C 109 °F (NIOSH, 2024) [1] CAMEO Chemicals
43 °C 109 °F (EPA, 1998) [1] CAMEO Chemicalscites U.S. Environmental Protection Agency. 1998. Extremely Hazardous Substances (EHS) Chemical Profiles and Emergency First Aid Guides. Washington, D.C.: U.S. Government Printing Office.
40.9 °Cshown 40.91 °C [6] Hazardous Substances Data Bank (HSDB)cites Kirk-Othmer Encyclopedia of Chemical Technology. 4th ed. Volumes 1: New York, NY. John Wiley and Sons, 1991-Present., p. V18 (1996) 592
41 °C 41 °C [3] ILO-WHO International Chemical Safety Cards (ICSCs)
43 °C 109 °F [4] Occupational Safety and Health Administration (OSHA)
40.9 °C 40.89 °C [7] PAC Chemical Database, U.S. Department of Energy
43 °C 109 °F [5] The National Institute for Occupational Safety and Health (NIOSH)
Boiling point: 181.75 °C @ 101.3 kPa[6]
8 values
6 of 6 sources agree on it (most common value).
Value As written Source
182 °C 360 °F at 760 mmHg (NTP, 1992) [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
182 °C 359 °F at 760 mmHg (NIOSH, 2024) [1] CAMEO Chemicals
181.7 °C 359.1 °F at 760 mmHg (EPA, 1998) [1] CAMEO Chemicalscites U.S. Environmental Protection Agency. 1998. Extremely Hazardous Substances (EHS) Chemical Profiles and Emergency First Aid Guides. Washington, D.C.: U.S. Government Printing Office.
181.8 °Cshown 181.75 °C @ 101.3 kPa [6] Hazardous Substances Data Bank (HSDB)cites Kirk-Othmer Encyclopedia of Chemical Technology. 4th ed. Volumes 1: New York, NY. John Wiley and Sons, 1991-Present., p. V18 (1996) 592
182 °C 182 °C [3] ILO-WHO International Chemical Safety Cards (ICSCs)
182 °C 359 °F [4] Occupational Safety and Health Administration (OSHA)
181.9 °C 181.87 °C @760 [mm Hg] [7] PAC Chemical Database, U.S. Department of Energy
182 °C 359 °F [5] The National Institute for Occupational Safety and Health (NIOSH)
Density: 1.0545 @ 45°C[7]
7 values
5 of 5 sources agree on it (most common value).
Value As written Source
– 1.04 at 105.8 °F (USCG, 1999) - Denser than water [1] CAMEO Chemicalscites U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office.
– 1.06 (NIOSH, 2024) - Denser than water [1] CAMEO Chemicals
– 1.0722 at 68 °F (EPA, 1998) - Denser than water [1] CAMEO Chemicalscites U.S. Environmental Protection Agency. 1998. Extremely Hazardous Substances (EHS) Chemical Profiles and Emergency First Aid Guides. Washington, D.C.: U.S. Government Printing Office.
– 1.06 g/cm³ [3] ILO-WHO International Chemical Safety Cards (ICSCs)
– 1.06 [4] Occupational Safety and Health Administration (OSHA)
–shown 1.0545 @ 45°C [7] PAC Chemical Database, U.S. Department of Energy
– 1.06 [5] The National Institute for Occupational Safety and Health (NIOSH)
5 more values were reported but failed the checks (unreadable or out of range), so they are not shown.
Solubility in water: Solubility in water, g/l at 20 °C: 84 (moderate)[3]
6 values
From ILO-WHO International Chemical Safety Cards (ICSCs), the most authoritative source here.
Value As written Source
– 50 to 100 mg/mL at 66 °F (NTP, 1992) [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
– 9 % at 77 °F (NIOSH, 2024) [1] CAMEO Chemicals
– 9 % at 77 °F (NIOSH, 2024) [1] CAMEO Chemicals
– For more Solubility (Complete) data for PHENOL (7 total), please visit the HSDB record page. [6] Hazardous Substances Data Bank (HSDB)
–shown Solubility in water, g/l at 20 °C: 84 (moderate) [3] ILO-WHO International Chemical Safety Cards (ICSCs)
– (77 °F): 9% [5] The National Institute for Occupational Safety and Health (NIOSH)
log P: 1.46[3]
2 values
2 of 2 sources agree on it (most common value).
Value As written Source
– Log Kow = 1.46 [6] Hazardous Substances Data Bank (HSDB)cites Hansch, C., Leo, A., D. Hoekman. Exploring QSAR - Hydrophobic, Electronic, and Steric Constants. Washington, DC: American Chemical Society., 1995., p. 20
–shown 1.46 [3] ILO-WHO International Chemical Safety Cards (ICSCs)
Vapor pressure: 0.3513 mmHg at 25 °C (77 °F, EPA 1998)[1]
6 values
3 of 4 sources agree on it (most common value).
Value As written Source
0.2 mmHg 0.2 mmHg at 68 °F [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
0.35 mmHg 0.35 mmHg at 77 °F (NTP, 1992) [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
0.3513 mmHgshown 0.3513 mmHg at 77 °F (EPA, 1998) [1] CAMEO Chemicalscites U.S. Environmental Protection Agency. 1998. Extremely Hazardous Substances (EHS) Chemical Profiles and Emergency First Aid Guides. Washington, D.C.: U.S. Government Printing Office.
0.35 mmHg 0.35 mm Hg @ 25 °C [6] Hazardous Substances Data Bank (HSDB)cites Jones AH; J Chem Eng Data 5: 196-200 (1960)
0.35 mmHg Vapor pressure, Pa at 20 °C: 47 [3] ILO-WHO International Chemical Safety Cards (ICSCs)
0.75 mmHg 0.75 [mm Hg] @34.1 °C [7] PAC Chemical Database, U.S. Department of Energy
3 more values were reported but failed the checks (unreadable or out of range), so they are not shown.
Flash point: 79.0 °C (174.2 °F, EPA 1998)[1]
9 values
5 of 5 sources agree on it (most common value).
Value As written Source
79 °C 175 °F (NTP, 1992) [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
79 °C 175 °F (NIOSH, 2024) [1] CAMEO Chemicals
79.0 °Cshown 174.2 °F (EPA, 1998) [1] CAMEO Chemicalscites U.S. Environmental Protection Agency. 1998. Extremely Hazardous Substances (EHS) Chemical Profiles and Emergency First Aid Guides. Washington, D.C.: U.S. Government Printing Office.
79 °C 175 °F [6] Hazardous Substances Data Bank (HSDB)cites Fire Protection Guide to Hazardous Materials. 13 ed. Quincy, MA: National Fire Protection Association, 2002., p. 325-97
79 °C 79 °C, (Closed cup) [6] Hazardous Substances Data Bank (HSDB)cites Fire Protection Guide to Hazardous Materials. 13 ed. Quincy, MA: National Fire Protection Association, 2002., p. 325-97
85 °C 85 °C, (Open cup) [6] Hazardous Substances Data Bank (HSDB)cites ITII. Toxic and Hazardous Industrial Chemicals Safety Manual. Tokyo, Japan: The International Technical Information Institute, 1988., p. 405
79 °C 79 °C c.c. [3] ILO-WHO International Chemical Safety Cards (ICSCs)
79 °C 175 °F [4] Occupational Safety and Health Administration (OSHA)
79 °C 175 °F [5] The National Institute for Occupational Safety and Health (NIOSH)
Autoignition temperature: 715 °C (1319 °F)[6]
4 values
3 of 3 sources agree on it (most common value).
Value As written Source
715 °C 1319 °F (USCG, 1999) [1] CAMEO Chemicalscites U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office.
715 °C 1319 °F (USCG, 1999) [1] CAMEO Chemicalscites U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office.
715 °Cshown 1319 °F (715 °C) [6] Hazardous Substances Data Bank (HSDB)cites Fire Protection Guide to Hazardous Materials. 13 ed. Quincy, MA: National Fire Protection Association, 2002., p. 325-97
715 °C 715 °C [3] ILO-WHO International Chemical Safety Cards (ICSCs)

Value	As written	Source
–	Phenol solution, [aqueous] is a white crystalline mass dissolved in an aqueous solution. Solution may be colorless to slightly pink in color with a distinctive phenol odor; sharp burning taste. Aqueous solution will be acidic and act as such. Toxic by ingestion, inhalation and skin absorption; strong irritant to tissues.	[1] CAMEO Chemicals
–	Phenol, liquid appears as a colorless liquid when pure, otherwise pink or red. Combustible. Flash point 175 °F. Must be heated before ignition may occur easily. Vapors are heavier than air. Corrosive to skin but because of anesthetic qualities will numb rather than burn. Upon contact skin may turn white. May be lethal by skin absorption. Does not react with water. Stable in normal transportation. Reactive with various chemicals and may be corrosive to lead, aluminum and its alloys, certain plastics, and rubber. Freezing point about 105 °F. Density 8.9 lb / gal. Used to make plastics, adhesives	[1] CAMEO Chemicals
–	Phenol, molten is the white crystalline solid shipped at an elevated temperature to form a semi-solid. It is very hot and may cause burns from contact and also may cause the ignition of combustible materials. It is toxic by ingestion, and inhalation of its fumes, and skin absorption. It may also be very irritating to skin and eyes. It is used to make other chemicals.	[1] CAMEO Chemicals
–	Phenol, solid appears as a solid melting at 110 °F. Colorless if pure, otherwise pink or red. Flash point 175 °F. Density 9.9 lb / gal. Vapors are heavier than air Corrosive to the skin (turning skin white) but because of its anesthetic quality numbs rather than burn. Lethal amounts can be absorbed through the skin. Used to make plastics and adhesives.	[1] CAMEO Chemicals
–	Dry Powder; Liquid; Large Crystals; Gas Vapor; Liquid; CBI	[2] EPA Chemical Data Reporting (CDR)
–	COLOURLESS-TO-YELLOW OR LIGHT PINK CRYSTALS WITH CHARACTERISTIC ODOUR.	[3] ILO-WHO International Chemical Safety Cards (ICSCs)
–	Colorless to light-pink, crystalline solid with a sweet, acrid odor.	[4] Occupational Safety and Health Administration (OSHA)
–	Colorless to light-pink, crystalline solid with a sweet, acrid odor. [Note: Phenol liquefies by mixing with about 8% water.]	[5] The National Institute for Occupational Safety and Health (NIOSH)
–	White crystalline mass of hygroscopic, translucent needle-shaped crystals; pink or red when impurities are present; darkens on exposure to light	[6] Hazardous Substances Data Bank (HSDB)cites Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V3 383
–	White, crystalline mass that turns pink or red if not perfectly pure or if under influence of light.	[6] Hazardous Substances Data Bank (HSDB)cites Lewis, R.J., Sr (Ed.). Hawley's Condensed Chemical Dictionary. 13th ed. New York, NY: John Wiley & Sons, Inc. 1997., p. 860
–	Colorless to light pink, interlaced, or separate, needleshaped crystals, or a ... light pink, crystalline mass	[6] Hazardous Substances Data Bank (HSDB)cites Osol, A. (ed.). Remington's Pharmaceutical Sciences. 16th ed. Easton, Pennsylvania: Mack Publishing Co., 1980., p. 1262
–shown	Colorless to light pink crystalline solid. [Note: Phenol liquefies by mixing with about 8% water.]	[6] Hazardous Substances Data Bank (HSDB)cites NIOSH. NIOSH Pocket Guide to Chemical Hazards. DHHS (NIOSH) Publication No. 94-116. Washington, D.C.: U.S. Government Printing Office, June 1994., p. 248

Value	As written	Source
–	Distinct aromatic, somewhat sickening sweet and acrid odor, discernable at 0.5 to 5 ppm	[6] Hazardous Substances Data Bank (HSDB)cites Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V4 383
–shown	Sweet, tarry odor	[6] Hazardous Substances Data Bank (HSDB)cites Kirk-Othmer Encyclopedia of Chemical Technology. 4th ed. Volumes 1: New York, NY. John Wiley and Sons, 1991-Present., p. V18 (2001) 592

Value	As written	Source
43 °C	109 °F (NTP, 1992)	[1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
43 °C	109 °F (NIOSH, 2024)	[1] CAMEO Chemicals
43 °C	109 °F (EPA, 1998)	[1] CAMEO Chemicalscites U.S. Environmental Protection Agency. 1998. Extremely Hazardous Substances (EHS) Chemical Profiles and Emergency First Aid Guides. Washington, D.C.: U.S. Government Printing Office.
40.9 °Cshown	40.91 °C	[6] Hazardous Substances Data Bank (HSDB)cites Kirk-Othmer Encyclopedia of Chemical Technology. 4th ed. Volumes 1: New York, NY. John Wiley and Sons, 1991-Present., p. V18 (1996) 592
41 °C	41 °C	[3] ILO-WHO International Chemical Safety Cards (ICSCs)
43 °C	109 °F	[4] Occupational Safety and Health Administration (OSHA)
40.9 °C	40.89 °C	[7] PAC Chemical Database, U.S. Department of Energy
43 °C	109 °F	[5] The National Institute for Occupational Safety and Health (NIOSH)

Value	As written	Source
182 °C	360 °F at 760 mmHg (NTP, 1992)	[1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
182 °C	359 °F at 760 mmHg (NIOSH, 2024)	[1] CAMEO Chemicals
181.7 °C	359.1 °F at 760 mmHg (EPA, 1998)	[1] CAMEO Chemicalscites U.S. Environmental Protection Agency. 1998. Extremely Hazardous Substances (EHS) Chemical Profiles and Emergency First Aid Guides. Washington, D.C.: U.S. Government Printing Office.
181.8 °Cshown	181.75 °C @ 101.3 kPa	[6] Hazardous Substances Data Bank (HSDB)cites Kirk-Othmer Encyclopedia of Chemical Technology. 4th ed. Volumes 1: New York, NY. John Wiley and Sons, 1991-Present., p. V18 (1996) 592
182 °C	182 °C	[3] ILO-WHO International Chemical Safety Cards (ICSCs)
182 °C	359 °F	[4] Occupational Safety and Health Administration (OSHA)
181.9 °C	181.87 °C @760 [mm Hg]	[7] PAC Chemical Database, U.S. Department of Energy
182 °C	359 °F	[5] The National Institute for Occupational Safety and Health (NIOSH)

Value	As written	Source
–	1.04 at 105.8 °F (USCG, 1999) - Denser than water	[1] CAMEO Chemicalscites U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office.
–	1.06 (NIOSH, 2024) - Denser than water	[1] CAMEO Chemicals
–	1.0722 at 68 °F (EPA, 1998) - Denser than water	[1] CAMEO Chemicalscites U.S. Environmental Protection Agency. 1998. Extremely Hazardous Substances (EHS) Chemical Profiles and Emergency First Aid Guides. Washington, D.C.: U.S. Government Printing Office.
–	1.06 g/cm³	[3] ILO-WHO International Chemical Safety Cards (ICSCs)
–	1.06	[4] Occupational Safety and Health Administration (OSHA)
–shown	1.0545 @ 45°C	[7] PAC Chemical Database, U.S. Department of Energy
–	1.06	[5] The National Institute for Occupational Safety and Health (NIOSH)

Value	As written	Source
–	50 to 100 mg/mL at 66 °F (NTP, 1992)	[1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
–	9 % at 77 °F (NIOSH, 2024)	[1] CAMEO Chemicals
–	9 % at 77 °F (NIOSH, 2024)	[1] CAMEO Chemicals
–	For more Solubility (Complete) data for PHENOL (7 total), please visit the HSDB record page.	[6] Hazardous Substances Data Bank (HSDB)
–shown	Solubility in water, g/l at 20 °C: 84 (moderate)	[3] ILO-WHO International Chemical Safety Cards (ICSCs)
–	(77 °F): 9%	[5] The National Institute for Occupational Safety and Health (NIOSH)

Value	As written	Source
–	Log Kow = 1.46	[6] Hazardous Substances Data Bank (HSDB)cites Hansch, C., Leo, A., D. Hoekman. Exploring QSAR - Hydrophobic, Electronic, and Steric Constants. Washington, DC: American Chemical Society., 1995., p. 20
–shown	1.46	[3] ILO-WHO International Chemical Safety Cards (ICSCs)

Value	As written	Source
0.2 mmHg	0.2 mmHg at 68 °F	[1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
0.35 mmHg	0.35 mmHg at 77 °F (NTP, 1992)	[1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
0.3513 mmHgshown	0.3513 mmHg at 77 °F (EPA, 1998)	[1] CAMEO Chemicalscites U.S. Environmental Protection Agency. 1998. Extremely Hazardous Substances (EHS) Chemical Profiles and Emergency First Aid Guides. Washington, D.C.: U.S. Government Printing Office.
0.35 mmHg	0.35 mm Hg @ 25 °C	[6] Hazardous Substances Data Bank (HSDB)cites Jones AH; J Chem Eng Data 5: 196-200 (1960)
0.35 mmHg	Vapor pressure, Pa at 20 °C: 47	[3] ILO-WHO International Chemical Safety Cards (ICSCs)
0.75 mmHg	0.75 [mm Hg] @34.1 °C	[7] PAC Chemical Database, U.S. Department of Energy

Value	As written	Source
79 °C	175 °F (NTP, 1992)	[1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
79 °C	175 °F (NIOSH, 2024)	[1] CAMEO Chemicals
79.0 °Cshown	174.2 °F (EPA, 1998)	[1] CAMEO Chemicalscites U.S. Environmental Protection Agency. 1998. Extremely Hazardous Substances (EHS) Chemical Profiles and Emergency First Aid Guides. Washington, D.C.: U.S. Government Printing Office.
79 °C	175 °F	[6] Hazardous Substances Data Bank (HSDB)cites Fire Protection Guide to Hazardous Materials. 13 ed. Quincy, MA: National Fire Protection Association, 2002., p. 325-97
79 °C	79 °C, (Closed cup)	[6] Hazardous Substances Data Bank (HSDB)cites Fire Protection Guide to Hazardous Materials. 13 ed. Quincy, MA: National Fire Protection Association, 2002., p. 325-97
85 °C	85 °C, (Open cup)	[6] Hazardous Substances Data Bank (HSDB)cites ITII. Toxic and Hazardous Industrial Chemicals Safety Manual. Tokyo, Japan: The International Technical Information Institute, 1988., p. 405
79 °C	79 °C c.c.	[3] ILO-WHO International Chemical Safety Cards (ICSCs)
79 °C	175 °F	[4] Occupational Safety and Health Administration (OSHA)
79 °C	175 °F	[5] The National Institute for Occupational Safety and Health (NIOSH)

Value	As written	Source
715 °C	1319 °F (USCG, 1999)	[1] CAMEO Chemicalscites U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office.
715 °C	1319 °F (USCG, 1999)	[1] CAMEO Chemicalscites U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office.
715 °Cshown	1319 °F (715 °C)	[6] Hazardous Substances Data Bank (HSDB)cites Fire Protection Guide to Hazardous Materials. 13 ed. Quincy, MA: National Fire Protection Association, 2002., p. 325-97
715 °C	715 °C	[3] ILO-WHO International Chemical Safety Cards (ICSCs)

Each value as its source reports it, with the source's number after it (listed under References). Where several sources report a property, the row shows the value most of them agree on, the rule the app uses; open the values to see every one.

Calculated

Heavy atoms: 7
Rings: 1
Aromatic rings: 1
Fraction sp³ carbons (Fsp3): 0
H-bond donors: 1
H-bond acceptors: 1
Rotatable bonds: 0
TPSA (Å²): 20.2
Formal charge: 0
XLogP3: 1.5 PubChem
Complexity: 46 PubChem
Stereocenters: None
Double-bond geometry: None specified
Point group: Cs of one 3D conformer with its hydrogens, by Athanor’s engine (as in the app)

Elemental analysis

C76.57%
H6.43%
O17.00%

Isotope pattern

Each peak is a nominal mass with its abundance-weighted exact mass, as a percentage of the tallest, from IUPAC natural isotope abundances.

Computed from the structure with RDKit 2026.09 when this page was built, beside PubChem's own computed values from its record; where the two differ, both are shown.

Predicted

log P: 1.39 Crippen (Wildman and Crippen 1999)
log S (water solubility): -1.93 ESOL (Delaney 2004), log mol/L
Synthetic accessibility: 1.18 SA score, 1 easy to 10 hard (Ertl and Schuffenhauer 2009)

Drug-likeness: Lipinski’s rule of five

Molecular weight ≤ 500: 94.11
log P ≤ 5 (Crippen): 1.39
H-bond donors ≤ 5: 1
H-bond acceptors ≤ 10: 1

Passes all four rules.

¹³C NMR shifts, predicted

Predictions, not measurements; each names its method. A measured log P, where a source reports one, is under Physical properties.

Safety

Danger

Harmonized EU classification (CLP Annex VI). Source [8].

Corrosive
Acute toxicity
Health hazard

NFPA 704[6]

H301Toxic if swallowed
H311Toxic in contact with skin
H314Causes severe skin burns and eye damage
H331Toxic if inhaled
H341Suspected of causing genetic defects

Precautionary statements: P203, P260, P261, P262, P264, P270, P271, P280, P301+P316, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P318, P319, P321, P330, P361+P364, P363, P403+P233, P405, P501

View all classifications (3)

[8] Regulation (EC) No 1272/2008 of the European Parliament and of the Council · DangerH301, H311, H314, H331, H341
[9] European Chemicals Agency (ECHA)This chemical does not meet GHS hazard criteria for < 0.1% (1 of 4205) of reports.
[9] European Chemicals Agency (ECHA) · 4,205 reports · DangerH301, H318, H331, H341, H373, H411

Exposure limits

PEL-TWA (8-Hour Time Weighted Average): 5 ppm (19mg/m³)[4]
PEL: TWA 5 ppm (19 mg/m3) [skin][5]
REL-TWA (Time Weighted Average): 5 ppm (19 mg/m³)[4]
REL-C (Ceiling): 15.6 ppm (60 mg/m³) [15 minutes][4]
REL: TWA 5 ppm (19 mg/m3) C 15.6 ppm (60 mg/m3) [15-minute] [skin][5]
TLV: 5 ppm as TWA; (skin); A4 (not classifiable as a human carcinogen); BEI issued.[3]

First aid

Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]: Refer to the "General First Aid" section. Specific First Aid: For corrosives, in case of contact, immediately flush skin or eyes with running water for at least 30 minutes. Additional flushing may be required. Removal of solidified molten material from skin requires medical assistance. (ERG, 2024)[1]
Eyes: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. Immediately transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. Skin: Immediately flood affected skin with water while removing and isolating all contaminated clothing.[1]
Excerpt from NIOSH Pocket Guide for Phenol: Eye: Irrigate immediately - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately. Skin: SOAP WASH immediately - If this chemical contacts the skin, immediately wash the contaminated skin with soap and water.[1]
Signs and Symptoms of Acute Phenol Exposure: Signs and symptoms of acute exposure to phenol may be severe, and range from tachycardia (rapid heart rate) and tachypnea (rapid respiratory rate) to hypotension (low blood pressure), weak pulse, cardiac failure, pulmonary edema, and respiratory arrest. Cardiac arrhythmias may be noted. Weakness, headache, dizziness, tinnitus (ringing in the ears), delirium, and shock are common. Seizures may often be followed by coma. Pallor, profuse sweating, dilated pupils, and a profound drop in body temperature may occur.[1]

Storage

Provision to contain effluent from fire extinguishing. Separated from strong oxidants and food and feedstuffs. Dry. Well closed. Store only in original container. Keep in a well-ventilated room. Store in an area without drain or sewer access.[3]
Phenol should be stored in closed containers in an area which is adequate to ensure that airborne phenol concentrations do not exceed 20 mg/cu m. Conditions shall be controlled to prevent overheating and the buildup of pressure in phenol containers. Storage tanks must be electrically grounded and bonded to transfer lines. Transfer and storage systems shall be designed and operated to prevent blockage by condensed phenol. Open flames are prohibited when drums of phenol are heated to melt the contents.[6]
Store in a cool, dry, well-ventilated location. Separate from oxidizers and acute fire hazards.[6]
Storage tanks should be equipped with heating coils which pass upward through the entire vessel ... . Tanks may be constructed by either welding or riveting. ... Underground tanks are not recommended.[6]

Incompatibilities

Addition of aluminum chloride to a large volume of recovered nitrobenzene containing 5% phenol caused a violent explosion. Experiment showed that mixtures containing all three components reacted violently at 120 °C.[6]
Uncontrolled contact of phenol with peroxodisulfuric acid may cause explosion.[6]
(A combination of phenol with calcium hypochlorite) ... Is an exothermic reaction producing toxic fumes, which may ignite.[6]
Mixtures of peroxymonosulfuric acid with phenol explode.[6]

Safety data sheets on the supplier’s page: Thermo Fisher Scientific, Yuhao Chemical, MolCore.

Always read the supplier’s safety data sheet before working with it.

Spectra

Experimental spectra held by these sources; each link opens the source's own record.

Literature

Reading PubChem, OpenAlex and GSRS…

Bioactivity

Reading ChEMBL…

References

[1]CAMEO Chemicals · Public domain (NOAA) · via PubChem · retrieved 2026-10-14
[2]EPA Chemical Data Reporting (CDR) · Public domain (US EPA) · via PubChem · retrieved 2026-10-14
[3]ILO-WHO International Chemical Safety Cards (ICSCs) · CC BY 4.0 · via PubChem · retrieved 2026-10-14
[4]Occupational Safety and Health Administration (OSHA) · Public domain (US DOL) · via PubChem · retrieved 2026-10-14
[5]The National Institute for Occupational Safety and Health (NIOSH) · Public domain (US CDC) · via PubChem · retrieved 2026-10-14
[6]Hazardous Substances Data Bank (HSDB) · Public domain (US NLM) · via PubChem · retrieved 2026-10-14
[7]PAC Chemical Database, U.S. Department of Energy · Public domain (US DOE) · via PubChem · retrieved 2026-10-14
[8]Regulation (EC) No 1272/2008 of the European Parliament and of the Council · EU reuse policy, CC BY 4.0 · via PubChem · retrieved 2026-10-14
[9]European Chemicals Agency (ECHA) · ECHA legal notice: reuse with acknowledgement · via PubChem · retrieved 2026-10-14
[10]Emergency Response Guidebook (ERG) · Public domain (US DOT) · via PubChem · retrieved 2026-10-14
[11]NMRShiftDB · Linked only · via PubChem · retrieved 2026-10-14
[12]Human Metabolome Database (HMDB) · Linked only · via PubChem · retrieved 2026-10-14
[13]SpectraBase · Linked only · via PubChem · retrieved 2026-10-14
[14]MassBank of North America (MoNA) · CC BY 4.0 · via PubChem · retrieved 2026-10-14
[15]NIST Mass Spectrometry Data Center · Linked only · via PubChem · retrieved 2026-10-14
[16]MassBank Europe · Linked only · via PubChem · retrieved 2026-10-14
·Calculated values: computed by Athanor with RDKit 2026.09 from the structure.
·Literature on PubChem

Data last updated 2026-10-14.