Hydrochloric acid
Athanor · official
ClH · 36.46 g/mol
IUPAC name: chlorane
Also called muriatic acid, hydrogen chloride, HCl
Names and identifiers
- IUPAC name
- chlorane
- Synonyms
- muriatic acid, hydrogen chloride, HCl
+ 37 more
Muriatic acid, chlorane, Chlorohydric acid, Anhydrous hydrochloric acid, Acide chlorhydrique, Chlorwasserstoff, Muriaticum acidum, Chloorwaterstof, Chlorowodor, Hydrogen chloride (HCl), Acido cloridrico, Aqueous hydrogen chloride, chlorure d'hydrogene, Baume hcl, Icon etch, Acido clorhidrico, Enplate po 236, Anhydrous hydrogen chloride, Chlorure d'hydrogene anhydre, Cloruro de hidrogeno anhidro, Hydrochloric acid, anhydrous, NSC-77365, cloruro de hidrogeno, Acidum hydrochloricum, EPA Pesticide Chemical Code 045901, INS NO.507, QTT17582CB, DTXSID2020711, CHEBI:17883, INS-507, E-507, Acid, Muriatic, Chloride, Hydrogen, Acidum Muriaticum, HEMMORHOIDS, RefChem:6646, 231-595-7
- Molecular formula
- ClH
- Empirical formula
- ClH
- Molecular weight
- 36.46 g/mol
- Exact mass
- 35.97668
- CAS number
- 7647-01-0
- PubChem CID
- 313
- Canonical SMILES
- Cl
- Isomeric SMILES
- Cl
- InChI
- InChI=1S/ClH/h1H
- InChIKey
- VEXZGXHMUGYJMC-UHFFFAOYSA-N
- Molfile
Names, InChI and the identifiers from PubChem, retrieved 2026-10-14.
Physical properties
- Appearance
- Hydrochloric acid, solution is a colorless watery liquid with a sharp, irritating odor. Consists of hydrogen chloride, a gas, dissolved in water. Sinks and mixes with water. Produces irritating vapor. (USCG, 1999)[1]
7 values
From CAMEO Chemicals, the most authoritative source here.
Value As written Source –shown Hydrochloric acid, solution is a colorless watery liquid with a sharp, irritating odor. Consists of hydrogen chloride, a gas, dissolved in water. Sinks and mixes with water. Produces irritating vapor. (USCG, 1999) [1] CAMEO Chemicalscites U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office. – Hydrogen chloride, anhydrous appears as a colorless gas with a sharp, pungent odor. Fumes strongly in moist air. Nonflammable. Corrosive to metals and tissues and irritating to the eyes and respiratory system. Heavier than air. Long-term inhalation of low concentrations or short-term inhalation of high concentrations has adverse health effects. Prolonged exposure to fire or intense heat may result in the violent rupture and rocketing of the container. Used in the manufacture of rubber, pharmaceuticals, chemicals, and in gasoline refining and metals processing. Rate of onset: Immediate Persi [1] CAMEO Chemicals – Hydrogen chloride, refrigerated liquid appears as a colorless liquid with a sharp, pungent odor. Vapors are heavier than air. Long-term inhalation of low concentrations of vapors or short-term inhalation of high concentrations has adverse health effects. Exposure of the container to intense heat may cause its violent rupture and rocketing. [1] CAMEO Chemicals – Liquid; Gas Vapor; Liquid; Liquid; Other Solid; CBI; Gas Vapor; Dry Powder; Wet Solid [2] EPA Chemical Data Reporting (CDR) – COLOURLESS COMPRESSED LIQUEFIED GAS WITH PUNGENT ODOUR. [3] ILO-WHO International Chemical Safety Cards (ICSCs) – Colorless to slightly yellow gas with a pungent, irritating odor. [4] Occupational Safety and Health Administration (OSHA) – Colorless to slightly yellow gas with a pungent, irritating odor. [Note: Shipped as a liquefied compressed gas.] [5] The National Institute for Occupational Safety and Health (NIOSH) - Odor
- Pungent, irritating odor[6]
- Melting point
- -114.17 °C[7]
6 values
5 of 5 sources agree on it (most common value).
Value As written Source −114.8 °C -174.6 °F (Melting point is -13.7 °F for a 39.17% weight/weight solution.) (EPA, 1998) [1] CAMEO Chemicalscites U.S. Environmental Protection Agency. 1998. Extremely Hazardous Substances (EHS) Chemical Profiles and Emergency First Aid Guides. Washington, D.C.: U.S. Government Printing Office. −114 °C -174 °F (NIOSH, 2024) [1] CAMEO Chemicals −114.2 °C -114.2 °C [3] ILO-WHO International Chemical Safety Cards (ICSCs) −114 °C -174 °F [4] Occupational Safety and Health Administration (OSHA) −114.2 °Cshown -114.17 °C [7] PAC Chemical Database, U.S. Department of Energy −114 °C -174 °F [5] The National Institute for Occupational Safety and Health (NIOSH) - Boiling point
- -85.1 °C[3]
7 values
5 of 5 sources agree on it (most common value).
Value As written Source 51 °C 123 °F at 760 mmHg (USCG, 1999) [1] CAMEO Chemicalscites U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office. −85.0 °C -121 °F at 760 mmHg (A constant boiling azeotrope with water containing 20.22% hydrogen chloride boils at 227 °F.) (EPA, 1998) [1] CAMEO Chemicalscites U.S. Environmental Protection Agency. 1998. Extremely Hazardous Substances (EHS) Chemical Profiles and Emergency First Aid Guides. Washington, D.C.: U.S. Government Printing Office. −85 °C -121 °F at 760 mmHg (NIOSH, 2024) [1] CAMEO Chemicals −85.1 °Cshown -85.1 °C [3] ILO-WHO International Chemical Safety Cards (ICSCs) −85 °C -121 °F [4] Occupational Safety and Health Administration (OSHA) −85 °C -85 °C @760 [mm Hg] [7] PAC Chemical Database, U.S. Department of Energy −85 °C -121 °F [5] The National Institute for Occupational Safety and Health (NIOSH) - Density
- 1.49 @25 °C[7]
3 values
Sources disagree; from PAC Chemical Database, U.S. Department of Energy, the most authoritative.
Value As written Source – 1.05 at 59 °F for 10.17% weight/weight solution (EPA, 1998) - Denser than water [1] CAMEO Chemicalscites U.S. Environmental Protection Agency. 1998. Extremely Hazardous Substances (EHS) Chemical Profiles and Emergency First Aid Guides. Washington, D.C.: U.S. Government Printing Office. –shown 1.49 @25 °C [7] PAC Chemical Database, U.S. Department of Energy – 1.27(relative gas density) [5] The National Institute for Occupational Safety and Health (NIOSH) 1 more value was reported but failed the checks (unreadable or out of range), so it is not shown.
- Solubility in water
- Solubility in water, g/100ml at 30 °C: 67 (moderate)[3]
4 values
From ILO-WHO International Chemical Safety Cards (ICSCs), the most authoritative source here.
Value As written Source – 82.3 g/100 g at 32 °F (NTP, 1992) [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina. – 67 % at 86 °F (NIOSH, 2024) [1] CAMEO Chemicals –shown Solubility in water, g/100ml at 30 °C: 67 (moderate) [3] ILO-WHO International Chemical Safety Cards (ICSCs) – (86 °F): 67% [5] The National Institute for Occupational Safety and Health (NIOSH) - log P
- 0.25[3]
- Vapor pressure
- 750 [mmHg] @-85.2 °C[7]
4 values
2 of 3 sources agree on it (most common value).
Value As written Source 32452 mmHg 32452 mmHg at 70 °F [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina. 760 mmHg 760 mmHg at -120.6 °F (NTP, 1992) [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina. 35424 mmHg 35,424 mm Hg at 25 °C [6] Hazardous Substances Data Bank (HSDB)cites Daubert, T.E., R.P. Danner. Physical and Thermodynamic Properties of Pure Chemicals Data Compilation. Washington, D.C.: Taylor and Francis, 1989. 750 mmHgshown 750 [mm Hg] @-85.2 °C [7] PAC Chemical Database, U.S. Department of Energy 4 more values were reported but failed the checks (unreadable or out of range), so they are not shown.
- Autoignition temperature
- Reported, but no value passed the checks.
The 2 values and why
- Not flammable (USCG, 1999) (could not be read; source [1])
- Not flammable (USCG, 1999) (could not be read; source [1])
- Viscosity
- 0.405 cP (liquid at 118.16 K)[6]
3 values
Only one source reports it.
Value As written Source –shown 0.405 cP (liquid at 118.16 K) [6] Hazardous Substances Data Bank (HSDB)cites Hisham MW, Bommaraju TV; Hydrogen Chloride. Kirk-Othmer Encyclopedia of Chemical Technology. (1999-2015). New York, NY: John Wiley & Sons. Online Posting Date: 28 Apr 2014 – 0.0131 cP (vapor at 273.06 K) [6] Hazardous Substances Data Bank (HSDB)cites Hisham MW, Bommaraju TV; Hydrogen Chloride. Kirk-Othmer Encyclopedia of Chemical Technology. (1999-2015). New York, NY: John Wiley & Sons. Online Posting Date: 28 Apr 2014 – 0.0253 cP (vapor at 523.2 K) [6] Hazardous Substances Data Bank (HSDB)cites Hisham MW, Bommaraju TV; Hydrogen Chloride. Kirk-Othmer Encyclopedia of Chemical Technology. (1999-2015). New York, NY: John Wiley & Sons. Online Posting Date: 28 Apr 2014 - Refractive index
- 1.0004456 (gas at 273.16 K)[6]
2 values
Only one source reports it.
Value As written Source – Index of refraction: 1.254 (liquid at 283.16 K) [6] Hazardous Substances Data Bank (HSDB)cites Hisham MW, Bommaraju TV; Hydrogen Chloride. Kirk-Othmer Encyclopedia of Chemical Technology. (1999-2015). New York, NY: John Wiley & Sons. Online Posting Date: 28 Apr 2014 –shown 1.0004456 (gas at 273.16 K) [6] Hazardous Substances Data Bank (HSDB)cites Hisham MW, Bommaraju TV; Hydrogen Chloride. Kirk-Othmer Encyclopedia of Chemical Technology. (1999-2015). New York, NY: John Wiley & Sons. Online Posting Date: 28 Apr 2014
Each value as its source reports it, with the source's number after it (listed under References). Where several sources report a property, the row shows the value most of them agree on, the rule the app uses; open the values to see every one.
Calculated
- Heavy atoms
- 1
- Rings
- 0
- Aromatic rings
- 0
- Fraction sp³ carbons (Fsp3)
- 0
- H-bond donors
- 0 computed here · PubChem 1
- H-bond acceptors
- 0
- Rotatable bonds
- 0
- TPSA (Ų)
- 0
- Formal charge
- 0
- XLogP3
- 0.8 PubChem
- Complexity
- 0 PubChem
- Stereocenters
- None
- Double-bond geometry
- None specified
- Point group
- C∞v of one 3D conformer with its hydrogens, by Athanor’s engine (as in the app)
Elemental analysis
- H2.76%
- Cl97.24%
Isotope pattern
Each peak is a nominal mass with its abundance-weighted exact mass, as a percentage of the tallest, from IUPAC natural isotope abundances.
Computed from the structure with RDKit 2026.09 when this page was built, beside PubChem's own computed values from its record; where the two differ, both are shown.
Predicted
- log P
- 0.42 Crippen (Wildman and Crippen 1999)
- log S (water solubility)
- -0.33 ESOL (Delaney 2004), log mol/L
- Synthetic accessibility
- 6.25 SA score, 1 easy to 10 hard (Ertl and Schuffenhauer 2009)
Drug-likeness: Lipinski’s rule of five
- Molecular weight ≤ 500: 36.46
- log P ≤ 5 (Crippen): 0.42
- H-bond donors ≤ 5: 0
- H-bond acceptors ≤ 10: 0
Passes all four rules.
Predictions, not measurements; each names its method. A measured log P, where a source reports one, is under Physical properties.
Safety
Danger
Harmonized EU classification (CLP Annex VI). Source [8].
Compressed gas
Corrosive
Acute toxicity
- H314Causes severe skin burns and eye damage
- H331Toxic if inhaled
Precautionary statements: P260, P261, P264, P271, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P363, P403+P233, P405, P501
View all classifications (4)
- [8] Regulation (EC) No 1272/2008 of the European Parliament and of the Council · DangerH314, H331
- [9] European Chemicals Agency (ECHA)This chemical does not meet GHS hazard criteria for < 0.1% (1 of 5109) of reports.
- [9] European Chemicals Agency (ECHA) · 5,109 reports · DangerH280, H290, H314, H318, H331, H335
- [6] Hazardous Substances Data Bank (HSDB) · DangerH280, H314, H318, H331
Exposure limits
First aid
- Inhalation: Remove person to fresh air; keep him warm and quiet and get medical attention immediately; start artificial respiration if breathing stops. Ingestion: Have person drink water or milk; do NOT induce vomiting. Eyes: Immediately flush with plenty of water for at least 15 min. And get medical attention; continue flushing for another 15 min. If physician does not arrive promptly. Skin: Immediately flush skin while removing contaminated clothing; get medical attention promptly; use soap and wash area for at least 15 min. (USCG, 1999)[1]
- Warning: Hydrogen chloride is extremely corrosive. Caution is advised. Signs and Symptoms of Acute Hydrogen Chloride Exposure: Signs and symptoms of acute ingestion of hydrogen chloride may be severe and include salivation, intense thirst, difficulty in swallowing, chills, pain, and shock. Oral, esophageal, and stomach burns are common. Vomitus generally has a coffee-ground appearance. The potential for circulatory collapse is high following ingestion of hydrogen chloride.[1]
- Excerpt from NIOSH Pocket Guide for Hydrogen chloride: Eye: ⢠irrigate immediately (solution) - If this chemical in solution contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately. ⢠frostbite - If eye tissue is frozen, seek medical attention immediately; if tissue is not frozen, immediately and thoroughly flush the eyes with large amounts of water for at least 15 minutes, occasionally lifting the lower and upper eyelids. If irritation, pain, swelling, lacrimation, or photophobia[1]
- General First Aid: · Call 911 or emergency medical service. · Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination. · Move victim to fresh air if it can be done safely. · Administer oxygen if breathing is difficult. · If victim is not breathing: -- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance. -- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped…[10]
Storage
- Cool. Fireproof if in building. Separated from food and feedstuffs and incompatible materials. See Chemical Dangers. Keep in a well-ventilated room.[3]
- Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): Gases[6]
- Store in cool, dry, well-ventilated location. Separate from oxidizing materials, organic materials, and alkalies. (hydrogen chloride, anhydrous hydrogen chloride, refrigerated liquid)[6]
- Store in a dry place no lower in tersperature than 10 °C (50 °F) or higher than 49 °C (120 °F). (emulso Germicidal Bowl Cleaner Disinfectant)[6]
Incompatibilities
- The aqueous solution is a strong acid. Corrosive fumes emitted on contact with air. Reacts violently with bases, oxidizers forming toxic chlorine gas. Reacts, often violently, with acetic anhydride, active metals, aliphatic amines, alkanolamines, alkylene oxides, aromatic amines, amides, 2-aminoethanol, ammonia, ammonium hydroxide, calcium phosphide, chlorosulfonic acid, ethylene diamine, ethyleneimine, epichlorohydrin, isocyanates, metal acetylides, oleum, organic anhydrides, perchloric acid, 3-propiolactone, uranium phosphide, sulfuric acid, vinyl acetate, vinylidene fluoride.[6]
- Hydrochloric acid and hydrogen chloride react violently with many metals, with the generation of highly flammable hydrogen gas, which may explode. Reaction with oxidizers such as permanganates, chlorates, chlorites, and hypochlorites may produce chlorine or bromine gas.[6]
- Anhydrous hydrogen chloride is rapidly absorbed in water to form corrosive hydrochloric acid. Aqueous hydrochloric acid solutions are quite reactive. Reacts vigorously with alkalies and with many organic materials. Strong oxidizing materials cause release of chlorine. (hydrogen chloride, anhydrous hydrogen chloride, refrigerated liquid)[6]
- Cesium acetylene carbide burns in hydrogen chloride gas.[6]
Safety data sheets on the supplier’s page: LGC Standards, Alfa Chemistry, Sigma-Aldrich.
Always read the supplier’s safety data sheet before working with it.
Spectra
- GC-MSNIST Mass Spectrometry Data Center · NIST Mass Spectrometry Data Center · SpectraBase (GC/MS)
- MS-MSHuman Metabolome Database (HMDB) (Linear Ion Trap · negative) · Human Metabolome Database (HMDB) (Linear Ion Trap · negative) · Human Metabolome Database (HMDB) (Linear Ion Trap · positive)
- Vapor Phase IRSpectraBase (DIGILAB FTS-14 · Vapor Phase)
Experimental spectra held by these sources; each link opens the source's own record.
Literature
Reading PubChem, OpenAlex and GSRS…
Bioactivity
Reading ChEMBL…
References
- [1]CAMEO Chemicals · Public domain (NOAA) · via PubChem · retrieved 2026-10-14
- [2]EPA Chemical Data Reporting (CDR) · Public domain (US EPA) · via PubChem · retrieved 2026-10-14
- [3]ILO-WHO International Chemical Safety Cards (ICSCs) · CC BY 4.0 · via PubChem · retrieved 2026-10-14
- [4]Occupational Safety and Health Administration (OSHA) · Public domain (US DOL) · via PubChem · retrieved 2026-10-14
- [5]The National Institute for Occupational Safety and Health (NIOSH) · Public domain (US CDC) · via PubChem · retrieved 2026-10-14
- [6]Hazardous Substances Data Bank (HSDB) · Public domain (US NLM) · via PubChem · retrieved 2026-10-14
- [7]PAC Chemical Database, U.S. Department of Energy · Public domain (US DOE) · via PubChem · retrieved 2026-10-14
- [8]Regulation (EC) No 1272/2008 of the European Parliament and of the Council · EU reuse policy, CC BY 4.0 · via PubChem · retrieved 2026-10-14
- [9]European Chemicals Agency (ECHA) · ECHA legal notice: reuse with acknowledgement · via PubChem · retrieved 2026-10-14
- [10]Emergency Response Guidebook (ERG) · Public domain (US DOT) · via PubChem · retrieved 2026-10-14
- [11]NIST Mass Spectrometry Data Center · Linked only · via PubChem · retrieved 2026-10-14
- [12]SpectraBase · Linked only · via PubChem · retrieved 2026-10-14
- [13]Human Metabolome Database (HMDB) · Linked only · via PubChem · retrieved 2026-10-14
- ·Calculated values: computed by Athanor with RDKit 2026.09 from the structure.
- ·Literature on PubChem
Data last updated 2026-10-14.
