Carbon tetrachloride
Athanor · official
CCl4 · 153.8 g/mol
IUPAC name: tetrachloromethane
Also called tetrachloromethane, carbon tet
Names and identifiers
- IUPAC name
- tetrachloromethane
- Synonyms
- tetrachloromethane, carbon tet, Tetrachloromethane
+ 37 more
Perchloromethane, Tetrasol, Benzinoform, Necatorine, Tetrafinol, Vermoestricid, Carbona, Univerm, Carbon tet, Methane, tetrachloro-, Methane tetrachloride, Flukoids, Necatorina, Tetraform, Carbon chloride, Tetrachlormethan, Tetrachloormetaan, Tetrachlorocarbon, Freon 10, Tetraclorometano, Tetrachloorkoolstof, Czterochlorek wegla, Halon 1040, Carbon chloride (CCl4), Chlorid uhlicity, R 10 (Refrigerant), Tetrachlorure de carbone, Tetracloruro di carbonio, RCRA waste number U211, Tetra, Tetrachlorkohlenstoff, tetra, ENT 4,705, CC m0, DTXSID8020250, ENT 27164, Halon 104, NSC-97063
- Molecular formula
- CCl4
- Empirical formula
- CCl4
- Molecular weight
- 153.8 g/mol
- Exact mass
- 153.87246
- CAS number
- 56-23-5
- PubChem CID
- 5943
- Canonical SMILES
- C(Cl)(Cl)(Cl)Cl
- Isomeric SMILES
- C(Cl)(Cl)(Cl)Cl
- InChI
- InChI=1S/CCl4/c2-1(3,4)5
- InChIKey
- VZGDMQKNWNREIO-UHFFFAOYSA-N
- Molfile
Names, InChI and the identifiers from PubChem, retrieved 2026-10-14.
Physical properties
- Appearance
- Colorless liquid[6]
6 values
From Hazardous Substances Data Bank (HSDB), the most authoritative source here.
Value As written Source – Carbon tetrachloride appears as a clear colorless liquid with a characteristic odor. Denser than water (13.2 lb / gal) and insoluble in water. Noncombustible. May cause illness by inhalation, skin absorption and/or ingestion. Used as a solvent, in the manufacture of other chemicals, as an agricultural fumigant, and for many other uses. [1] CAMEO Chemicals – Liquid [2] EPA Chemical Data Reporting (CDR) – COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. [3] ILO-WHO International Chemical Safety Cards (ICSCs) – Clear liquid with a characteristic odor. [4] Occupational Safety and Health Administration (OSHA) – Colorless liquid with a characteristic ether-like odor. [5] The National Institute for Occupational Safety and Health (NIOSH) –shown Colorless liquid [6] Hazardous Substances Data Bank (HSDB)cites NIOSH. NIOSH Pocket Guide to Chemical Hazards. Department of Health & Human Services, Centers for Disease Control & Prevention. National Institute for Occupational Safety & Health. DHHS (NIOSH) Publication No. 2010-168 (2010). Available from: https://www.cdc.gov/niosh/npg - Odor
- Sweet[6]
4 values
From Hazardous Substances Data Bank (HSDB), the most authoritative source here.
Value As written Source –shown Sweet [6] Hazardous Substances Data Bank (HSDB)cites NOAA; CAMEO Chemicals. Database of Hazardous Materials. Carbon tetrachloride (56-23-5). Natl Ocean Atmos Admin, Off Resp Rest; NOAA Ocean Serv. Available from, as of Mar 16, 2018: https://cameochemicals.noaa.gov/ – Characteristic, ether-like odor [6] Hazardous Substances Data Bank (HSDB)cites NIOSH. NIOSH Pocket Guide to Chemical Hazards. Department of Health & Human Services, Centers for Disease Control & Prevention. National Institute for Occupational Safety & Health. DHHS (NIOSH) Publication No. 2010-168 (2010). Available from: https://www.cdc.gov/niosh/npg – Sweetish, distinctive odor [6] Hazardous Substances Data Bank (HSDB)cites Larranaga, M.D., Lewis, R.J. Sr., Lewis, R.A.; Hawley's Condensed Chemical Dictionary 16th Edition. John Wiley & Sons, Inc. Hoboken, NJ 2016., p. 263 – Characteristic non-irritant odor [6] Hazardous Substances Data Bank (HSDB)cites Holbrook MT; Carbon Tetrachloride. Kirk-Othmer Encyclopedia of Chemical Technology. (1999-2018). New York, NY: John Wiley & Sons. Online Posting Date: 4 Dec 2000 - Melting point
- -22.62 °C[7]
5 values
5 of 5 sources agree on it (most common value).
Value As written Source −23 °C -9 °F (NTP, 1992) [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina. −23 °C -23 °C [3] ILO-WHO International Chemical Safety Cards (ICSCs) −23 °C -9 °F [4] Occupational Safety and Health Administration (OSHA) −22.6 °Cshown -22.62 °C [7] PAC Chemical Database, U.S. Department of Energy −23 °C -9 °F [5] The National Institute for Occupational Safety and Health (NIOSH) - Boiling point
- 76.7 °C (170.1 °F) at 760 mmHg (NTP, 1992)[1]
5 values
5 of 5 sources agree on it (most common value).
Value As written Source 76.7 °Cshown 170.1 °F at 760 mmHg (NTP, 1992) [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina. 76.7 °C 76.7 °C [3] ILO-WHO International Chemical Safety Cards (ICSCs) 76.7 °C 170.1 °F [4] Occupational Safety and Health Administration (OSHA) 76.8 °C 76.8 °C @760 [mm Hg] [7] PAC Chemical Database, U.S. Department of Energy 77 °C 170 °F [5] The National Institute for Occupational Safety and Health (NIOSH) - Density
- 1.5940 @ 20°C[7]
5 values
5 of 5 sources agree on it (most common value).
Value As written Source – 1.59 at 68 °F (USCG, 1999) - Denser than water [1] CAMEO Chemicalscites U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office. – Relative density (water = 1): 1.59 (20 °C) [3] ILO-WHO International Chemical Safety Cards (ICSCs) – 1.59 [4] Occupational Safety and Health Administration (OSHA) –shown 1.5940 @ 20°C [7] PAC Chemical Database, U.S. Department of Energy – 1.59 [5] The National Institute for Occupational Safety and Health (NIOSH) 7 more values were reported but failed the checks (unreadable or out of range), so they are not shown.
- Solubility in water
- Solubility in water, mg/l at 20 °C: 800 (very slightly soluble)[3]
6 values
From ILO-WHO International Chemical Safety Cards (ICSCs), the most authoritative source here.
Value As written Source – less than 1 mg/mL at 70 °F (NTP, 1992) [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina. – In water, 793 mg/L at 25 °C [6] Hazardous Substances Data Bank (HSDB)cites Horvath AL; Halogenated hydrocarbons: solubility-miscibility with water. New York, NY: Marcel Dekker, Inc pp. 889 (1982) – In water, 1160 mg/L at 25 °C, 800 mg/L at 20 °C [6] Hazardous Substances Data Bank (HSDB)cites Verschueren, K. Handbook of Environmental Data on Organic Chemicals. Volumes 1-2. 4th ed. John Wiley & Sons. New York, NY. 2001, p. 438 – Soluble in naphtha [6] Hazardous Substances Data Bank (HSDB)cites ITII. Toxic and Hazarous Industrial Chemicals Safety Manual. Tokyo, Japan: The International Technical Information Institute, 1982., p. 109 –shown Solubility in water, mg/l at 20 °C: 800 (very slightly soluble) [3] ILO-WHO International Chemical Safety Cards (ICSCs) – 0.05% [5] The National Institute for Occupational Safety and Health (NIOSH) - log P
- 2.64[3]
2 values
Sources disagree; from ILO-WHO International Chemical Safety Cards (ICSCs), the most authoritative.
Value As written Source – log Kow = 2.83 [6] Hazardous Substances Data Bank (HSDB)cites Hansch, C., Leo, A., D. Hoekman. Exploring QSAR - Hydrophobic, Electronic, and Steric Constants. Washington, DC: American Chemical Society., 1995., p. 3 –shown 2.64 [3] ILO-WHO International Chemical Safety Cards (ICSCs) - Vapor pressure
- 115 mmHg at 25 °C[6]
5 values
2 of 4 sources agree on it (most common value).
Value As written Source 91 mmHg 91 mmHg at 68 °F [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina. 113 mmHg 113 mmHg at 77 °F (NTP, 1992) [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina. 115 mmHgshown 115 mm Hg at 25 °C [6] Hazardous Substances Data Bank (HSDB)cites Boublik T et al; The vapor pressures of pure substances: selected values of the temperature dependence of the vapour pressures of some pure substances in the normal and low pressure region. Vol. 17. Amsterdam, Netherlands: Elsevier Sci. Publ (1984) 92 mmHg Vapor pressure, kPa at 20 °C: 12.2 [3] ILO-WHO International Chemical Safety Cards (ICSCs) 75 mmHg 75 [mm Hg] @15.8 °C [7] PAC Chemical Database, U.S. Department of Energy 2 more values were reported but failed the checks (unreadable or out of range), so they are not shown.
- Autoignition temperature
- Reported, but no value passed the checks.
The value and why
- Not flammable (USCG, 1999) (could not be read; source [1])
- Viscosity
- 2.03 mPa*s at -23 °C[3]
2 values
2 of 2 sources agree on it (most common value).
Value As written Source – 2.03X10-3 Pa.s at 250.00 K [6] Hazardous Substances Data Bank (HSDB)cites Daubert, T.E., R.P. Danner. Physical and Thermodynamic Properties of Pure Chemicals Data Compilation. Washington, D.C.: Taylor and Francis, 1989. –shown 2.03 mPa*s at -23 °C [3] ILO-WHO International Chemical Safety Cards (ICSCs)
Each value as its source reports it, with the source's number after it (listed under References). Where several sources report a property, the row shows the value most of them agree on, the rule the app uses; open the values to see every one.
Calculated
- Heavy atoms
- 5
- Rings
- 0
- Aromatic rings
- 0
- Fraction sp³ carbons (Fsp3)
- 1
- H-bond donors
- 0
- H-bond acceptors
- 0
- Rotatable bonds
- 0
- TPSA (Ų)
- 0
- Formal charge
- 0
- XLogP3
- 2.8 PubChem
- Complexity
- 19 PubChem
- Stereocenters
- None
- Double-bond geometry
- None specified
- Point group
- Td of one 3D conformer with its hydrogens, by Athanor’s engine (as in the app)
Elemental analysis
- C7.81%
- Cl92.19%
Isotope pattern
Each peak is a nominal mass with its abundance-weighted exact mass, as a percentage of the tallest, from IUPAC natural isotope abundances.
Computed from the structure with RDKit 2026.09 when this page was built, beside PubChem's own computed values from its record; where the two differ, both are shown.
Predicted
- log P
- 2.55 Crippen (Wildman and Crippen 1999)
- log S (water solubility)
- -2.4 ESOL (Delaney 2004), log mol/L
- Synthetic accessibility
- 2.86 SA score, 1 easy to 10 hard (Ertl and Schuffenhauer 2009)
Drug-likeness: Lipinski’s rule of five
- Molecular weight ≤ 500: 153.82
- log P ≤ 5 (Crippen): 2.55
- H-bond donors ≤ 5: 0
- H-bond acceptors ≤ 10: 0
Passes all four rules.
¹³C NMR shifts, predicted
Predictions, not measurements; each names its method. A measured log P, where a source reports one, is under Physical properties.
Safety
Danger
Harmonized EU classification (CLP Annex VI). Source [8].
Acute toxicity
Health hazard
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H331Toxic if inhaled
- H351Suspected of causing cancer
- H412Harmful to aquatic life with long lasting effects
- H420Harms public health and the environment by destroying ozone in the upper atmosphere
Precautionary statements: P203, P260, P261, P262, P264, P270, P271, P273, P280, P301+P316, P302+P352, P304+P340, P316, P318, P319, P321, P330, P361+P364, P403+P233, P405, P501, P502
View all classifications (3)
- [8] Regulation (EC) No 1272/2008 of the European Parliament and of the Council · DangerH301, H311, H331, H351, H412, H420
- [9] European Chemicals Agency (ECHA) · 601 reports · DangerH301+H311+H331, H301, H311, H317, H331, H351, H372, H412, H420
- [6] Hazardous Substances Data Bank (HSDB) · DangerH301, H311, H317, H331, H351, H372, H402, H412, H420
Exposure limits
- PEL-TWA (8-Hour Time Weighted Average): 10 ppm[4]
- PEL-C (Ceiling): 25 ppm [5 min in any 4 hrs]; 200 ppm (Peak)[4]
- PEL: TWA 10 ppm C 25 ppm 200 ppm (5-minute maximum peak in any 4 hours) See Appendix G[5]
- REL-STEL (Short Term Exposure Limit): 2 ppm (12.6 mg/m³) [60 minutes][4]
- REL: Ca ST 2 ppm (12.6 mg/m3) [60-minute] See Appendix A[5]
- TLV: 5 ppm as TWA; 10 ppm as STEL; (skin); A2 (suspected human carcinogen).[3]
First aid
- Eyes: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. Immediately transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. Skin: Immediately flood affected skin with water while removing and isolating all contaminated clothing.[1]
- General First Aid: · Call 911 or emergency medical service. · Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination. · Move victim to fresh air if it can be done safely. · Administer oxygen if breathing is difficult. · If victim is not breathing: -- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance. -- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped…[10]
- (General first aid procedures) Eye: Irrigate immediately - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately. Skin: Soap wash immediately - If this chemical contacts the skin, immediately wash the contaminated skin with soap and water.[5]
- Remove immediately from exposure. Fresh air, rest. Artificial respiration may be needed. Refer immediately for medical attention.[3]
Storage
- Well closed. Cool. Separated from food and feedstuffs and metals. See Chemical Dangers. Ventilation along the floor. Store in an area without drain or sewer access.[3]
- Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.[6]
- Store in a cool, dry, well-ventilated location. Separate from alkali metals.[6]
- Store in a secure poison location. Prior to working with carbon tetrachloride you should be trained on its proper handling and storage. Store in tightly closed containers in a cool, well-ventilated area. Carbon tetrachloride must be stored to avoid contact with chemically active metals, such as sodium, potassium, and magnesium, since violent reactions occur. ... A regulated, marked area should be established where this chemical is handled, used, or stored in compliance with OSHA Standard 1910.1045.[6]
Incompatibilities
- Incompatible materials: Strong oxidizing agents.[6]
- A reaction between allyl alcohol and carbon tetrachloride produces trichlorobutylene epoxide (oxide) and dichlorobutylene epoxide (oxide), a mixture which during distillation proved to be unstable and detonated in the still.[6]
- A bomb containing powdered aluminum and carbon tetrachloride exploded violently when heated to 153 °C. A mixture of powdered aluminum and carbon tetrachloride in a ball mill exploded.[6]
- A violent reaction occurred when small chunks of barium were cleaned by submerging in chemically pure carbon tetrachloride.[6]
Safety data sheets on the supplier’s page: CATO Research Chemicals Inc., Yuhao Chemical, LGC Standards.
Always read the supplier’s safety data sheet before working with it.
Spectra
- 13C NMRHazardous Substances Data Bank (HSDB) · Human Metabolome Database (HMDB) (Varian · 25.16 MHz · CDCl3) · SpectraBase
- GC-MSHuman Metabolome Database (HMDB) (EI-B · positive) · Human Metabolome Database (HMDB) (EI-B · positive) · Human Metabolome Database (HMDB) (EI-B · positive) · Human Metabolome Database (HMDB) (EI-B · positive) · Human Metabolome Database (HMDB) (EI-B · positive) · Human Metabolome Database (HMDB) (EI-B · positive)
- Other MSHazardous Substances Data Bank (HSDB) · MassBank Europe (JEOL JMS-01-SG · EI-B · POSITIVE) · MassBank Europe (JEOL JMS-D-3000 · EI-B · POSITIVE) · MassBank Europe (HITACHI RMU-7M · EI-B · POSITIVE)
- UVHazardous Substances Data Bank (HSDB)
- IRHazardous Substances Data Bank (HSDB)
- FTIRSpectraBase (NEAT)
- ATR-IRSpectraBase (Bio-Rad FTS · ATR-Neat (DuraSamplIR II))
- Vapor Phase IRSpectraBase (DIGILAB FTS-14 · Vapor Phase)
- RamanHazardous Substances Data Bank (HSDB) · SpectraBase (Thermo Nicolet FT-Raman 960 · FT-Raman)
Experimental spectra held by these sources; each link opens the source's own record.
Literature
Reading PubChem, OpenAlex and GSRS…
Bioactivity
Reading ChEMBL…
References
- [1]CAMEO Chemicals · Public domain (NOAA) · via PubChem · retrieved 2026-10-14
- [2]EPA Chemical Data Reporting (CDR) · Public domain (US EPA) · via PubChem · retrieved 2026-10-14
- [3]ILO-WHO International Chemical Safety Cards (ICSCs) · CC BY 4.0 · via PubChem · retrieved 2026-10-14
- [4]Occupational Safety and Health Administration (OSHA) · Public domain (US DOL) · via PubChem · retrieved 2026-10-14
- [5]The National Institute for Occupational Safety and Health (NIOSH) · Public domain (US CDC) · via PubChem · retrieved 2026-10-14
- [6]Hazardous Substances Data Bank (HSDB) · Public domain (US NLM) · via PubChem · retrieved 2026-10-14
- [7]PAC Chemical Database, U.S. Department of Energy · Public domain (US DOE) · via PubChem · retrieved 2026-10-14
- [8]Regulation (EC) No 1272/2008 of the European Parliament and of the Council · EU reuse policy, CC BY 4.0 · via PubChem · retrieved 2026-10-14
- [9]European Chemicals Agency (ECHA) · ECHA legal notice: reuse with acknowledgement · via PubChem · retrieved 2026-10-14
- [10]Emergency Response Guidebook (ERG) · Public domain (US DOT) · via PubChem · retrieved 2026-10-14
- [11]Human Metabolome Database (HMDB) · Linked only · via PubChem · retrieved 2026-10-14
- [12]SpectraBase · Linked only · via PubChem · retrieved 2026-10-14
- [13]MassBank of North America (MoNA) · CC BY 4.0 · via PubChem · retrieved 2026-10-14
- [14]NIST Mass Spectrometry Data Center · Linked only · via PubChem · retrieved 2026-10-14
- [15]MassBank Europe · Linked only · via PubChem · retrieved 2026-10-14
- ·Calculated values: computed by Athanor with RDKit 2026.09 from the structure.
- ·Literature on PubChem
Data last updated 2026-10-14.
