Acetic acid

Athanor · official

C₂H₄O₂ · 60.05 g/mol

Also called AcOH, ethanoic acid, glacial acetic acid, vinegar acid, E260

Solvents Reagents

Open in Athanor

Drawn from its SMILES with RDKit

DangerFlammable liquid and vapor · Causes severe skin burns and eye damage

Names and identifiers

IUPAC name: acetic acid
Synonyms: AcOH, ethanoic acid, glacial acetic acid
+ 39 more
vinegar acid, E260, Ethylic acid, Vinegar acid, Acetic acid glacial, Glacial acetic acid, Acetic acid, glacial, Methanecarboxylic acid, Acetasol, Essigsaeure, Acide acetique, Aci-jel, Azijnzuur, Aceticum acidum, Kyselina octova, Acido acetico, Octowy kwas, HOAc, Orlex, ethoic acid, Ethanoic acid monomer, FEMA No. 2006, Orthoacetic acid, Acetopyrine, Acopyrine, Ethanoat, Acidum aceticum glaciale, Acidum aceticum, DTXSID5024394, NSC-132953, NSC-406306, INS NO.260, Acetic acid 0.25% in plastic container, INS-260, Q40Q9N063P, E-260, NSC-111201, NSC-112209, NSC-115870
Molecular formula: C₂H₄O₂
Empirical formula: CH₂O
Molecular weight: 60.05 g/mol
Exact mass: 60.02113
CAS number: 64-19-7
PubChem CID: 176
Canonical SMILES: CC(=O)O
Isomeric SMILES: CC(=O)O
InChI: InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)
InChIKey: QTBSBXVTEAMEQO-UHFFFAOYSA-N
Molfile

Names, InChI and the identifiers from PubChem, retrieved 2026-10-14.

Physical properties

TemperaturePressureDensity

Appearance: Clear, colorless liquid[6]
9 values
From Hazardous Substances Data Bank (HSDB), the most authoritative source here.
Value As written Source
– Acetic acid, glacial appears as a clear colorless liquid with a strong odor of vinegar. Flash point 104 °F. Density 8.8 lb / gal. Corrosive to metals and tissue. Used to make other chemicals, as a food additive, and in petroleum production. [1] CAMEO Chemicals
– Acetic acid, solution, more than 10% but not more than 80% acid appears as a colorless aqueous solution. Smells like vinegar. Corrosive to metals and tissue. [1] CAMEO Chemicals
– Acetic acid, solution, more than 80% acid is a clear colorless aqueous solution with a pungent odor. [1] CAMEO Chemicals
– Liquid; Other Solid; Liquid; CBI [2] EPA Chemical Data Reporting (CDR)
– COLOURLESS LIQUID WITH PUNGENT ODOUR. [3] ILO-WHO International Chemical Safety Cards (ICSCs)
– Colorless liquid or crystals with a sour, vinegar-like odor. [4] Occupational Safety and Health Administration (OSHA)
– Colorless liquid or crystals with a sour, vinegar-like odor. [Note: Pure compound is a solid below 62 °F. Often used in an aqueous solution.] [5] The National Institute for Occupational Safety and Health (NIOSH)
–shown Clear, colorless liquid [6] Hazardous Substances Data Bank (HSDB)cites Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 7
– Colorless liquid or crystals (Note: Pure compound is a solid below 62 degrees F). Often used in an aqueous solution). [6] Hazardous Substances Data Bank (HSDB)cites NIOSH. NIOSH Pocket Guide to Chemical Hazards. Department of Health & Human Services, Centers for Disease Control & Prevention. National Institute for Occupational Safety & Health. DHHS (NIOSH) Publication No. 2010-168 (2010). Available from: https://www.cdc.gov/niosh/npg
Odor: Sour, vinegar-like odor[6]
Melting point: 16.635 °C[6]
6 values
6 of 6 sources agree on it (most common value).
Value As written Source
16.6 °C 61.9 °F (NTP, 1992) [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
16.6 °Cshown 16.635 °C [6] Hazardous Substances Data Bank (HSDB)cites Wagner FS; Acetic Acid. Kirk-Othmer Encyclopedia of Chemical Technology. (1999-2014). New York, NY: John Wiley & Sons. Online Posting Date: Apr 29, 2014.
16.7 °C 16.7 °C [3] ILO-WHO International Chemical Safety Cards (ICSCs)
17 °C 62 °F [4] Occupational Safety and Health Administration (OSHA)
16.6 °C 16.64 °C [7] PAC Chemical Database, U.S. Department of Energy
17 °C 62 °F [5] The National Institute for Occupational Safety and Health (NIOSH)
Boiling point: 117.9 °C @760 [mmHg][7]
5 values
5 of 5 sources agree on it (most common value).
Value As written Source
118 °C 244 °F at 760 mmHg (NTP, 1992) [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
118 °C 118 °C [3] ILO-WHO International Chemical Safety Cards (ICSCs)
118 °C 244 °F [4] Occupational Safety and Health Administration (OSHA)
117.9 °Cshown 117.9 °C @760 [mm Hg] [7] PAC Chemical Database, U.S. Department of Energy
118 °C 244 °F [5] The National Institute for Occupational Safety and Health (NIOSH)
Density: 1.049 @ 20°C[7]
5 values
5 of 5 sources agree on it (most common value).
Value As written Source
– 1.051 at 68 °F (USCG, 1999) - Denser than water [1] CAMEO Chemicalscites U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office.
– Relative density (water = 1): 1.05 [3] ILO-WHO International Chemical Safety Cards (ICSCs)
– 1.05 [4] Occupational Safety and Health Administration (OSHA)
–shown 1.049 @ 20°C [7] PAC Chemical Database, U.S. Department of Energy
– 1.05 [5] The National Institute for Occupational Safety and Health (NIOSH)
Solubility in water: Solubility in water: miscible[3]
4 values
From ILO-WHO International Chemical Safety Cards (ICSCs), the most authoritative source here.
Value As written Source
– greater than or equal to 100 mg/mL at 73 °F (NTP, 1992) [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
– Miscible with glycerol; insoluble in carbon disulfide [6] Hazardous Substances Data Bank (HSDB)cites Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 7
–shown Solubility in water: miscible [3] ILO-WHO International Chemical Safety Cards (ICSCs)
– Miscible [5] The National Institute for Occupational Safety and Health (NIOSH)
log P: -0.17[3]
2 values
2 of 2 sources agree on it (most common value).
Value As written Source
– log Kow = -0.17 [6] Hazardous Substances Data Bank (HSDB)cites Hansch, C., Leo, A., D. Hoekman. Exploring QSAR - Hydrophobic, Electronic, and Steric Constants. Washington, DC: American Chemical Society., 1995., p. 4
–shown -0.17 [3] ILO-WHO International Chemical Safety Cards (ICSCs)
pKa: pKa = 4.76 at 25 °C[6]
Vapor pressure: 11.4 [mmHg] @20 °C[7]
5 values
3 of 4 sources agree on it (most common value).
Value As written Source
11.4 mmHg 11.4 mmHg at 68 °F [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
20 mmHg 20 mmHg at 86 °F (NTP, 1992) [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
15.7 mmHg 15.7 mm Hg at 25 °C /Extrapolated/ [6] Hazardous Substances Data Bank (HSDB)cites Daubert, T.E., R.P. Danner. Physical and Thermodynamic Properties of Pure Chemicals Data Compilation. Washington, D.C.: Taylor and Francis, 1989.
11 mmHg Vapor pressure, kPa at 20 °C: 1.5 [3] ILO-WHO International Chemical Safety Cards (ICSCs)
11.4 mmHgshown 11.4 [mm Hg] @20 °C [7] PAC Chemical Database, U.S. Department of Energy
2 more values were reported but failed the checks (unreadable or out of range), so they are not shown.
Flash point: 39 °C (103 °F) Closed cup[6]
8 values
5 of 5 sources agree on it (most common value).
Value As written Source
40 °C 104 °F (NTP, 1992) [1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
39 °C 103 °F (NFPA, 2010) [1] CAMEO Chemicalscites National Fire Protection Association. 2010. Fire Protection Guide to Hazardous Materials, 14th edition, edited by Guy R. Colonna. Quincy, MA: National Fire Protection Association. Note that this information is subject to the copyright restrictions of the organization that provided the data.
39 °Cshown 103 °F (39 °C) Closed cup [6] Hazardous Substances Data Bank (HSDB)cites National Fire Protection Association; Fire Protection Guide to Hazardous Materials. 14TH Edition, Quincy, MA 2010, p. 325-9
44 °C 112 °F (open cup) [6] Hazardous Substances Data Bank (HSDB)cites U.S. Coast Guard, Department of Transportation. CHRIS - Hazardous Chemical Data. Volume II. Washington, D.C.: U.S. Government Printing Office, 1984-5.
40 °C 104 °F (closed cup) [6] Hazardous Substances Data Bank (HSDB)cites U.S. Coast Guard, Department of Transportation. CHRIS - Hazardous Chemical Data. Volume II. Washington, D.C.: U.S. Government Printing Office, 1984-5.
39 °C 39 °C c.c. [3] ILO-WHO International Chemical Safety Cards (ICSCs)
39 °C 103 °F [4] Occupational Safety and Health Administration (OSHA)
39 °C 103 °F [5] The National Institute for Occupational Safety and Health (NIOSH)
Autoignition temperature: 485 °C[3]
3 values
Sources disagree; from ILO-WHO International Chemical Safety Cards (ICSCs), the most authoritative.
Value As written Source
516 °C 961 °F (USCG, 1999) [1] CAMEO Chemicalscites U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office.
464 °C 867 °F (463 °C) [6] Hazardous Substances Data Bank (HSDB)cites National Fire Protection Association; Fire Protection Guide to Hazardous Materials. 14TH Edition, Quincy, MA 2010, p. 325-9
485 °Cshown 485 °C [3] ILO-WHO International Chemical Safety Cards (ICSCs)

Value	As written	Source
–	Acetic acid, glacial appears as a clear colorless liquid with a strong odor of vinegar. Flash point 104 °F. Density 8.8 lb / gal. Corrosive to metals and tissue. Used to make other chemicals, as a food additive, and in petroleum production.	[1] CAMEO Chemicals
–	Acetic acid, solution, more than 10% but not more than 80% acid appears as a colorless aqueous solution. Smells like vinegar. Corrosive to metals and tissue.	[1] CAMEO Chemicals
–	Acetic acid, solution, more than 80% acid is a clear colorless aqueous solution with a pungent odor.	[1] CAMEO Chemicals
–	Liquid; Other Solid; Liquid; CBI	[2] EPA Chemical Data Reporting (CDR)
–	COLOURLESS LIQUID WITH PUNGENT ODOUR.	[3] ILO-WHO International Chemical Safety Cards (ICSCs)
–	Colorless liquid or crystals with a sour, vinegar-like odor.	[4] Occupational Safety and Health Administration (OSHA)
–	Colorless liquid or crystals with a sour, vinegar-like odor. [Note: Pure compound is a solid below 62 °F. Often used in an aqueous solution.]	[5] The National Institute for Occupational Safety and Health (NIOSH)
–shown	Clear, colorless liquid	[6] Hazardous Substances Data Bank (HSDB)cites Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 7
–	Colorless liquid or crystals (Note: Pure compound is a solid below 62 degrees F). Often used in an aqueous solution).	[6] Hazardous Substances Data Bank (HSDB)cites NIOSH. NIOSH Pocket Guide to Chemical Hazards. Department of Health & Human Services, Centers for Disease Control & Prevention. National Institute for Occupational Safety & Health. DHHS (NIOSH) Publication No. 2010-168 (2010). Available from: https://www.cdc.gov/niosh/npg

Value	As written	Source
16.6 °C	61.9 °F (NTP, 1992)	[1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
16.6 °Cshown	16.635 °C	[6] Hazardous Substances Data Bank (HSDB)cites Wagner FS; Acetic Acid. Kirk-Othmer Encyclopedia of Chemical Technology. (1999-2014). New York, NY: John Wiley & Sons. Online Posting Date: Apr 29, 2014.
16.7 °C	16.7 °C	[3] ILO-WHO International Chemical Safety Cards (ICSCs)
17 °C	62 °F	[4] Occupational Safety and Health Administration (OSHA)
16.6 °C	16.64 °C	[7] PAC Chemical Database, U.S. Department of Energy
17 °C	62 °F	[5] The National Institute for Occupational Safety and Health (NIOSH)

Value	As written	Source
118 °C	244 °F at 760 mmHg (NTP, 1992)	[1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
118 °C	118 °C	[3] ILO-WHO International Chemical Safety Cards (ICSCs)
118 °C	244 °F	[4] Occupational Safety and Health Administration (OSHA)
117.9 °Cshown	117.9 °C @760 [mm Hg]	[7] PAC Chemical Database, U.S. Department of Energy
118 °C	244 °F	[5] The National Institute for Occupational Safety and Health (NIOSH)

Value	As written	Source
–	1.051 at 68 °F (USCG, 1999) - Denser than water	[1] CAMEO Chemicalscites U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office.
–	Relative density (water = 1): 1.05	[3] ILO-WHO International Chemical Safety Cards (ICSCs)
–	1.05	[4] Occupational Safety and Health Administration (OSHA)
–shown	1.049 @ 20°C	[7] PAC Chemical Database, U.S. Department of Energy
–	1.05	[5] The National Institute for Occupational Safety and Health (NIOSH)

Value	As written	Source
–	greater than or equal to 100 mg/mL at 73 °F (NTP, 1992)	[1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
–	Miscible with glycerol; insoluble in carbon disulfide	[6] Hazardous Substances Data Bank (HSDB)cites Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 7
–shown	Solubility in water: miscible	[3] ILO-WHO International Chemical Safety Cards (ICSCs)
–	Miscible	[5] The National Institute for Occupational Safety and Health (NIOSH)

Value	As written	Source
–	log Kow = -0.17	[6] Hazardous Substances Data Bank (HSDB)cites Hansch, C., Leo, A., D. Hoekman. Exploring QSAR - Hydrophobic, Electronic, and Steric Constants. Washington, DC: American Chemical Society., 1995., p. 4
–shown	-0.17	[3] ILO-WHO International Chemical Safety Cards (ICSCs)

Value	As written	Source
11.4 mmHg	11.4 mmHg at 68 °F	[1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
20 mmHg	20 mmHg at 86 °F (NTP, 1992)	[1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
15.7 mmHg	15.7 mm Hg at 25 °C /Extrapolated/	[6] Hazardous Substances Data Bank (HSDB)cites Daubert, T.E., R.P. Danner. Physical and Thermodynamic Properties of Pure Chemicals Data Compilation. Washington, D.C.: Taylor and Francis, 1989.
11 mmHg	Vapor pressure, kPa at 20 °C: 1.5	[3] ILO-WHO International Chemical Safety Cards (ICSCs)
11.4 mmHgshown	11.4 [mm Hg] @20 °C	[7] PAC Chemical Database, U.S. Department of Energy

Value	As written	Source
40 °C	104 °F (NTP, 1992)	[1] CAMEO Chemicalscites National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
39 °C	103 °F (NFPA, 2010)	[1] CAMEO Chemicalscites National Fire Protection Association. 2010. Fire Protection Guide to Hazardous Materials, 14th edition, edited by Guy R. Colonna. Quincy, MA: National Fire Protection Association. Note that this information is subject to the copyright restrictions of the organization that provided the data.
39 °Cshown	103 °F (39 °C) Closed cup	[6] Hazardous Substances Data Bank (HSDB)cites National Fire Protection Association; Fire Protection Guide to Hazardous Materials. 14TH Edition, Quincy, MA 2010, p. 325-9
44 °C	112 °F (open cup)	[6] Hazardous Substances Data Bank (HSDB)cites U.S. Coast Guard, Department of Transportation. CHRIS - Hazardous Chemical Data. Volume II. Washington, D.C.: U.S. Government Printing Office, 1984-5.
40 °C	104 °F (closed cup)	[6] Hazardous Substances Data Bank (HSDB)cites U.S. Coast Guard, Department of Transportation. CHRIS - Hazardous Chemical Data. Volume II. Washington, D.C.: U.S. Government Printing Office, 1984-5.
39 °C	39 °C c.c.	[3] ILO-WHO International Chemical Safety Cards (ICSCs)
39 °C	103 °F	[4] Occupational Safety and Health Administration (OSHA)
39 °C	103 °F	[5] The National Institute for Occupational Safety and Health (NIOSH)

Value	As written	Source
516 °C	961 °F (USCG, 1999)	[1] CAMEO Chemicalscites U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office.
464 °C	867 °F (463 °C)	[6] Hazardous Substances Data Bank (HSDB)cites National Fire Protection Association; Fire Protection Guide to Hazardous Materials. 14TH Edition, Quincy, MA 2010, p. 325-9
485 °Cshown	485 °C	[3] ILO-WHO International Chemical Safety Cards (ICSCs)

Each value as its source reports it, with the source's number after it (listed under References). Where several sources report a property, the row shows the value most of them agree on, the rule the app uses; open the values to see every one.

Calculated

Heavy atoms: 4
Rings: 0
Aromatic rings: 0
Fraction sp³ carbons (Fsp3): 0.5
H-bond donors: 1
H-bond acceptors: 1 computed here · PubChem 2
Rotatable bonds: 0
TPSA (Å²): 37.3
Formal charge: 0
XLogP3: -0.2 PubChem
Complexity: 31 PubChem
Stereocenters: None
Double-bond geometry: None specified
Point group: Cs of one 3D conformer with its hydrogens, by Athanor’s engine (as in the app)

Elemental analysis

C40.00%
H6.71%
O53.28%

Isotope pattern

Each peak is a nominal mass with its abundance-weighted exact mass, as a percentage of the tallest, from IUPAC natural isotope abundances.

Computed from the structure with RDKit 2026.09 when this page was built, beside PubChem's own computed values from its record; where the two differ, both are shown.

Predicted

log P: 0.09 Crippen (Wildman and Crippen 1999)
log S (water solubility): -0.27 ESOL (Delaney 2004), log mol/L
Synthetic accessibility: 1.51 SA score, 1 easy to 10 hard (Ertl and Schuffenhauer 2009)

Drug-likeness: Lipinski’s rule of five

Molecular weight ≤ 500: 60.05
log P ≤ 5 (Crippen): 0.09
H-bond donors ≤ 5: 1
H-bond acceptors ≤ 10: 1

Passes all four rules.

¹³C NMR shifts, predicted

Predictions, not measurements; each names its method. A measured log P, where a source reports one, is under Physical properties.

Safety

Danger

Harmonized EU classification (CLP Annex VI). Source [8].

Flammable
Corrosive

NFPA 704[6]

H226Flammable liquid and vapor
H314Causes severe skin burns and eye damage

Precautionary statements: P210, P233, P240, P241, P242, P243, P260, P264, P280, P301+P330+P331, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P321, P363, P370+P378, P403+P235, P405, P501

View all classifications (4)

[8] Regulation (EC) No 1272/2008 of the European Parliament and of the Council · DangerH226, H314
[9] European Chemicals Agency (ECHA)This chemical does not meet GHS hazard criteria for < 0.1% (3 of 5076) of reports.
[9] European Chemicals Agency (ECHA) · 5,076 reports · DangerH226, H318
[6] Hazardous Substances Data Bank (HSDB) · DangerH226, H314, H318

Exposure limits

PEL-TWA (8-Hour Time Weighted Average): 10 ppm (25 mg/m³)[4]
PEL: TWA 10 ppm (25 mg/m3)[5]
REL-STEL (Short Term Exposure Limit): 15 ppm (37 mg/m³)[4]
REL: TWA 10 ppm (25 mg/m3) ST 15 ppm (37 mg/m3)[5]
TLV: 10 ppm as TWA; 15 ppm as STEL[3]
IDLH: 50 ppm (NIOSH, 2024)[1]

First aid

Eyes: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. Immediately transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. Skin: Immediately flood affected skin with water while removing and isolating all contaminated clothing.[1]
Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]: Refer to the "General First Aid" section. Specific First Aid: For corrosives, in case of contact, immediately flush skin or eyes with running water for at least 30 minutes. Additional flushing may be required. Removal of solidified molten material from skin requires medical assistance. (ERG, 2024)[1]
Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]: Refer to the "General First Aid" section. Specific First Aid: For corrosives, in case of contact, immediately flush skin or eyes with running water for at least 30 minutes. Additional flushing may be required. In case of burns, immediately cool affected skin for as long as possible with cold water. Do not remove clothing if adhering to skin. (ERG, 2024)[1]
General First Aid: · Call 911 or emergency medical service. · Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination. · Move victim to fresh air if it can be done safely. · Administer oxygen if breathing is difficult. · If victim is not breathing: -- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance. -- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped…[10]

Storage

Fireproof. Separated from food and feedstuffs, strong oxidants, strong acids and strong bases. Store only in original container. Well closed. Keep in a well-ventilated room. Store in an area without drain or sewer access.[3]
Store in a dry, well-ventilated place. Separate from oxidizing materials and alkaline substances.[6]
Fireproof. Separate from food and feedstuffs. Keep in a well-ventilated room.[6]
... Quantities greater than 1 liter should be stored in tightly sealed metal containers in areas separate from oxidizers.[6]

Incompatibilities

Cooling is necessary to prevent possible explosion from contact of potassium permanganate (or the calcium or sodium salts) with acetic acid[6]
Liquid acetic acid will attack some forms of plastics, rubber, and coatings.[6]
An explosion occurred during initial heating up of a large volume of glacial acetic acid being treated with chromium trioxide. This was attributed to violent interaction of solid chromium trioxide and liquid acetic acid on a hot, exposed steam coil, and subsequent initiation of an explosive mixture of acetic acid vapor and air. The risk has been obviated by using a solution of dichromate in sulfuric acid as oxidant, in place of chromium trioxide.[6]
For more Hazardous Reactivities and Incompatibilities (Complete) data for acetic ACID (22 total), please visit the HSDB record page.[6]

Safety data sheets on the supplier’s page: AA BLOCKS, Sigma-Aldrich, Oakwood Products.

Always read the supplier’s safety data sheet before working with it.

Spectra

Experimental spectra held by these sources; each link opens the source's own record.

Literature

Reading PubChem, OpenAlex and GSRS…

Bioactivity

Reading ChEMBL…

References

[1]CAMEO Chemicals · Public domain (NOAA) · via PubChem · retrieved 2026-10-14
[2]EPA Chemical Data Reporting (CDR) · Public domain (US EPA) · via PubChem · retrieved 2026-10-14
[3]ILO-WHO International Chemical Safety Cards (ICSCs) · CC BY 4.0 · via PubChem · retrieved 2026-10-14
[4]Occupational Safety and Health Administration (OSHA) · Public domain (US DOL) · via PubChem · retrieved 2026-10-14
[5]The National Institute for Occupational Safety and Health (NIOSH) · Public domain (US CDC) · via PubChem · retrieved 2026-10-14
[6]Hazardous Substances Data Bank (HSDB) · Public domain (US NLM) · via PubChem · retrieved 2026-10-14
[7]PAC Chemical Database, U.S. Department of Energy · Public domain (US DOE) · via PubChem · retrieved 2026-10-14
[8]Regulation (EC) No 1272/2008 of the European Parliament and of the Council · EU reuse policy, CC BY 4.0 · via PubChem · retrieved 2026-10-14
[9]European Chemicals Agency (ECHA) · ECHA legal notice: reuse with acknowledgement · via PubChem · retrieved 2026-10-14
[10]Emergency Response Guidebook (ERG) · Public domain (US DOT) · via PubChem · retrieved 2026-10-14
[11]NMRShiftDB · Linked only · via PubChem · retrieved 2026-10-14
[12]Human Metabolome Database (HMDB) · Linked only · via PubChem · retrieved 2026-10-14
[13]SpectraBase · Linked only · via PubChem · retrieved 2026-10-14
[14]MassBank of North America (MoNA) · CC BY 4.0 · via PubChem · retrieved 2026-10-14
[15]NIST Mass Spectrometry Data Center · Linked only · via PubChem · retrieved 2026-10-14
[16]MassBank Europe · Linked only · via PubChem · retrieved 2026-10-14
·Calculated values: computed by Athanor with RDKit 2026.09 from the structure.
·Literature on PubChem

Data last updated 2026-10-14.